 | | Vol. 9.08 – 11 March, 2024 |
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| Muscleblind-like 1 (MBNL1) gain- and loss-of-function mouse models were studied at several developmental time points and in surgical models of heart regeneration.
[Circulation] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers investigated the role of mechanistic target of rapamycin complex 1 (mTORC1) and potential underlying mechanisms in isoproterenol-induced cardiomyocyte necrosis.
[Physiological Reports] |
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| The authors demonstrated that mutant SPN1 failed to oligomerize leading to cytoplasmic aggregation in patients’ primary fibroblasts and CRISPR/Cas9-mediated mutant cell lines.
[Nature Communications] |
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| A new cryoinjury model revealed that several myomeres efficiently regenerated within one month after wounding the zebrafish caudal peduncle.
[NPJ Regenerative Medicine] |
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| Scientists generated a skeletal-muscle-specific feline leukemia virus subgroup C receptor 1a (FLVCR1a) knockout mouse model and showed that, by sustaining heme synthesis, FLVCR1a contributed to determine the energy phenotype in skeletal muscle cells and to modulate satellite cell differentiation and muscle regeneration.
[Cell Reports] |
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| Researchers investigated the functions of human β defensin-3 in asthma progression. Blood samples from asthmatic and healthy children were collected.
[Molecular Immunology] |
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| Investigators describe the roles of ectodysplasin A2 receptor signaling in muscle pathophysiology, including muscle atrophy, insulin resistance, and aging-related sarcopenia.
[Trends in Molecular Medicine] |
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| The authors summarize the latest understanding of the molecular mechanisms by which smooth muscle cell-mineralocorticoid receptor contributes to regulation of vasomotor function and blood pressure, and more.
[Hypertension] |
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| Professor Dale Martin’s research lab is a recipient of a $125,000 ALS Canada-Brain Canada 2023 Discovery Grant. As an Assistant Professor in Biology, Martin’s research lab is dedicated to identifying new therapeutic targets for ALS.
[University of Waterloo] |
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| April 22 – 25, 2024
Baltimore, Maryland, United States |
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| | French National Institute for Health Research (INSERM) – Nantes, France |
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| | Pennington Biomedical Research Center – Baton Rouge, Louisiana, United States |
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| | Johns Hopkins Medicine Pathology – Baltimore, Maryland, United States |
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| | UC Davis – Davis, California, United States |
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| | Baylor College of Medicine – Houston, Texas, United States |
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