 | | Vol. 9.10 – 25 March, 2024 |
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| Using chemoinformatic analysis, the authors identified the 13–amino acid form of the peptide hormone apelin as a candidate for systemic stimulation of skeletal muscle endothelial cells.
[Science Translational Medicine] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators generated zebrafish heme oxygenase 1 (HMOX1) mutants using CRISPR/Cas9 genome editing technology. Deletion of hmox1a increased cardiac output and further induced hypertrophy in adults.
[Journal of Cellular and Molecular Medicine] |
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| A nanobody based affinity-purification/mass spectrometry strategy was employed for a detailed characterization of the MEF2A interactome.
[Molecular and Cellular Biology] |
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| Researchers implicated the ceramide synthases (CERS) 1 enzyme of the de novo sphingolipid synthesis pathway in the pathogenesis of age-related skeletal muscle impairment.
[eLife] |
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| Investigators developed monocarboxylate transporter 4 (MCT4) knockout mice and confirmed that a lack of MCT4 indeed resulted in pronounced lactate accumulation in skeletal muscle during high-intensity exercise.
[Journal Of Physiology] |
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| The authors investigated the 2.5-year impact of bronchial thermoplasty on airway smooth muscle mass and clinical parameters by paired data analysis in 22 patients.
[Thorax] |
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| Scientists investigated the mechanism of focal adhesion kinase (FAK)-dependent hypoxia-induced proliferation on human pulmonary artery smooth muscle cells.
[Cts-Clinical And Translational Science] |
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| Investigators discuss the similarities and differences in bridging integrator 1 (BIN1)’s functions in cardiac and skeletal muscle, along with its associated diseases and potential therapies.
[Trends in Molecular Medicine] |
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| A new major project supported by a Chan Zuckerberg Initiative grant will help bring the technology to shape muscle cells, blood vessels, and nerves into any pattern to fruition, offering revolutionary potential for treating neuromuscular disorders and other diseases.
[USC Viterbi School of Engineering] |
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| April 15 – 18, 2024
Herrenhausen Palace, Germany |
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| | Sapienza University – Rome, Italy |
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| | Brown University – Providence, Rhode Island, United States |
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| | French National Institute for Health Research (INSERM) – Nantes, France |
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| | Johns Hopkins Medicine Pathology – Baltimore, Maryland, United States |
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| | UC Davis – Davis, California, United States |
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