 | | Vol. 16.46 – 23 November, 2022 |
| |
|
|
| Researchers demonstrated in amyloid-β precursor protein transgenic mice and in patients with Alzheimer’s disease that medin co-localized with vascular amyloid-β deposits, and that in mice, medin deficiency reduced vascular amyloid-β deposition by half.
[Nature] |
|
|
|
 | | PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| Human H-ferritin (HFn), regorafenib (REGO), and Cu2+ were rationally designed as a brain-targeted nanoplatform, fulfilling the task of site-specific delivery and manipulating autophagy and cuproptosis against glioblastoma multiforme.
[Small] |
|
|
|
| Using human GABAergic projection neurons derived from human inducible pluripotent stem cells and embryonic stem cells in vitro, scientists tested ketamine effects on the growth cones and synapses in developing GABAergic neurons.
[Molecular Psychiatry] |
|
|
|
| Researchers used human cortical organoids to study the effects of alcohol on neurogenesis and validated our findings in primary human fetal neurons.
[Molecular Psychiatry] |
|
|
|
| Scientists characterized the structural and functional interaction between CBP/EP300 and heat-shock factor 2 (HSF2), a tuner of brain cortical development and major player in prenatal stress responses in the neocortex.
[Nature Communications] |
|
|
|
| Researchers showed that CRHR1 was required for the maintenance of neural stem cell properties, as assessed by in vitro neurosphere assays and cell distribution in the embryonic cortical layers following in utero electroporation.
[EMBO Reports] |
|
|
|
| Investigators highlighted the important role of the tyrosine hydroxylase–dopamine pathway in the pathogenesis of Parkinson’s disease.
[Cellular and Molecular Life Sciences] |
|
|
|
| Scientists investigated the impact of diesel exhaust particulate extract exposure on the brain and the mechanisms by which microglia and astroglia might mediate neuronal changes.
[Scientific Reports] |
|
|
|
| Investigators analyzed protein expression of retinal progenitor cell transcription factors and cell cycle regulators in rodent Müller glia in vivo and in vitro, focusing on their age- and cell-cycle-related expression changes.
[Scientific Reports] |
|
|
|
|
| The authors cover the range of injury to oligodendrocytes (OLs) and intrinsic versus extrinsic influences, and reflect on how this knowledge may be harnessed for therapeutic development.
[Communications Biology] |
|
|
|
| Investigators compare the view on microglia plasticity based on classical studies and on high-resolution ‘omic’ analyses to better understand their role in brain metastases and their impact on this complex multidimensional microenvironment.
[Histology and Histopathology] |
|
|
|
|
| AB Science SA announced that it had received an IND approval letter from the FDA to initiate Phase III study in patients with mild to moderate Alzheimer’s disease
[AB Science SA] |
|
|
|
| PerkinElmer, Inc. announced that the FDA had authorized the marketing of the EONI™ SCID-SMA assay kit for in vitro diagnostic use by certified laboratories for the simultaneous detection of spinal muscular atrophy (SMA) and severe combined immunodeficiency (SCID) in newborns.
[PerkinElmer, Inc.] |
|
|
|
|
| December 7 – 9, 2022
Geneva, Switzerland |
|
|
|
|
|
| | University of Texas Health Science Center – San Antonio, Texas, United States |
|
|
|
| | Baylor College of Medicine – Houston, Texas, United States |
|
|
|
| | Georgia Institute of Technology – Atlanta, Georgia, United States |
|
|
|
| | National Institute on Drug Abuse – Baltimore, Maryland, United States |
|
|
|
| | STEMCELL Technologies, Inc. – Boston, Massachusetts, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
