 | | Vol. 16.49 – 14 December, 2022 |
| |
|
|
| Scientists explored the use of alginate hydrogels as a Matrigel substitute in spinal cord organoid generation and found that alginate encapsulation reduced organoid size variability by preventing organoid aggregation.
[Advanced Healthcare Materials] |
|
|
|
 | | PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| Investigators evaluated the roles of BUD13, CDK12, and MBNL1 in regulating the vasculogenic mimicry formation of glioblastoma. BUD13 and CDK12 were upregulated and MBNL1 was downregulated in glioblastoma tissues and cells.
[Cell Death & Disease] |
|
|
|
| Researchers analyzed two brain calcification families and identified calcification co-segregated biallelic variants in the CMPK2 gene that disrupted mitochondrial functions.
[Cell Discovery] |
|
|
|
| Scientists characterized LTr1 as a novel anti-glioma agent and demonstrated its potent inhibition on the viability of human glioma cell lines.
[Acta Pharmacologica Sinica] |
|
|
|
| Researchers used a translational approach to assess the utility of neurofilament light (NFL) chains as a biomarker of paclitaxel-induced peripheral neuropathy in a human cell model and in ovarian cancer patients by measuring NFL in medium from human induced pluripotent stem-cell derived sensory neurons.
[Pain] |
|
|
|
| Histone deacetylases and microglial marker levels were examined in microglial cells after inducing senescence in vitro and in mouse and human hippocampal biopsies in vivo, using quantitative real-time PCR.
[Expert Opinion On Therapeutic Targets] |
|
|
|
| Based on the cytotoxic properties of aporphine compounds, researchers evaluated the biological effect of 12 compounds obtained through total synthesis of (±)-apomorphine hydrochloride against glioblastoma cells.
[Scientific Reports] |
|
|
|
| Investigators developed a protocol for human proprioceptive sensory neuron (pSN) differentiation to recreate pSN connections with skeletal muscle cells on a microfluidic chip and evaluate the differences in pSN in healthy and amyotrophic lateral sclerosis disease cells.
[Scientific Reports] |
|
|
|
| IL1RAP expression was found to be upregulated in spinal cord injury (SCI) mice spinal cord, SCI astrocytes, and lipopolysaccharide-stimulated normal human astrocytes.
[Neurochemical Research] |
|
|
|
|
| Scientists review the current methods used to generate microglia-containing human brain organoids (MC-HBOs) and provide opinions on the use of MC-HBOs for disease modeling and functional studies.
[Molecular Psychiatry] |
|
|
|
| The authors summarize key findings in central nervous system inflammation, effects on various neuronal populations, as well as accompanying peripheral immune changes which are implicated in the view of Parkinson’s disease as a disease of chronic inflammation.
[Neurobiology of Disease] |
|
|
|
|
| ClearPoint Neuro, Inc. announced enrollment of the first patient in a glioblastoma clinical trial using the ClearPoint Prism™ Neuro Laser Therapy System at Skåne University Hospital in Lund, Sweden.
[ClearPoint Neuro, Inc.] |
|
|
|
| Cerecin Inc. announced they had received authorization from the US FDA for an IND application for CER-0001 in Infantile Spasm, also referred to as West Syndrome.
[Cerecin, Inc.] |
|
|
|
|
| January 24 – 26, 2023
Boston, Massachusetts, United States |
|
|
|
|
|
| | University of California Irvine – Irvine, California, United States |
|
|
|
| | VIB-UAntwerp – Antwerp, Belgium |
|
|
|
| | Center for Nanomedicine and Tissue Engineering – Milan, Italy |
|
|
|
| | University of Melbourne – Melbourne, Victoria, Australia |
|
|
|
| | STEMCELL Technologies, Inc. – Boston, Massachusetts, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
