 | | Vol. 17.02 – 18 January, 2023 |
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| Researchers showed that, upon injury, adaptive responses to the microbiota directly promoted sensory neuron regeneration.
[Cell] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists described a novel neuronal zipcode identification protocol called N-zip that can identify zip codes across hundreds of 3′ untranslated regions.
[Nature Neuroscience] |
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| Investigators reported the presence of SARS-CoV-2 in first and second-trimester fetal brain tissue in association with cortical hemorrhages.
[Brain] |
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| The authors described ferritinophagy in isocitrate dehydrogenase (NADP(+)) 1 mutant gliomas with mechanistic details. They suggested that the PRMT1-PTX3 ferritinophagy regulatory circuit could be exploited for therapeutic gains.
[Autophagy] |
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| Scientists analyzed TCGA databases and found that co-mutations of PTEN and TP53 were most significantly enriched in human high-grade gliomas.
[Cancer Research] |
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| Researchers established the molecular mechanisms of interferon in stem cells and interferons as genuine regulators of stem cell homeostasis and a potential therapeutic target to repair the aging brain.
[Embo Molecular Medicine] |
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| Researchers used multiple approaches to show for the first time that SerineS129 functioned as a physiological regulator of neuronal activity.
[Npj Parkinson’s Disease] |
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| Scientists examined and clarified the abnormality of the cortical neuron phenotypes by generating Bloom Syndrome-induced pluripotent stem cells.
[Journal Of Human Genetics] |
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| Investigators examined the effects of a monoclonal antibody against (Pro)renin receptor on gliomagenesis. Human glioma cell lines, U251MG and U87MG, and a glioma stem cell line, MGG23, were used for the in vitro study.
[Scientific Reports] |
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| Researchers discuss blood-to-brain communication from a systems physiology perspective with an emphasis on blood-derived signals as potent drivers of both age-related brain dysfunction and brain rejuvenation.
[Nature Neuroscience] |
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| The authors summarize clinical and animal studies on inflammation in neural circuits related to anxiety and depression and the evidence that neuromodulation therapies regulate neuroinflammation in the treatment of neurological diseases.
[Translational Psychiatry] |
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| Clearmind Medicine, Inc. announced additional positive pre-clinical results in its ongoing series of research studies conducted to illuminate the tremendous potential of MEAI and its effect on substance-use disorder.
[Clearmind Medicine, Inc.] |
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| Day One Biopharmaceuticals announced positive topline results from the ongoing, open-label, pivotal Phase II FIREFLY-1 trial evaluating the investigational agent, tovorafenib, as a monotherapy in recurrent or progressive pediatric low-grade glioma.
[Day One Pharmaceuticals, Inc.] |
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| March 6 – 8, 2023
Paris, France |
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| | University of Melbourne – Melbourne, Victoria, Australia |
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| | Midwestern University – Glendale, Arizona, United States |
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| | The University of Southern Denmark – Odense, Denmark |
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| | Pompeu Fabra University – Barcelona, Spain |
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| | Baylor College of Medicine – Houston, Texas, United States |
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