 | | Vol. 17.30 – 2 August, 2023 |
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| Researchers found that both polypyrimidine tract binding protein 1 (PTBP1) and PTBP2 proteins were coexpressed in adult sensory and motor neurons, with PTBP2 restricted mainly to the nucleus, while PTBP1 also showed axonal localization.
[Science Advances] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Single-cell mass cytometry analysis revealed prominent expression of α5 integrin in microglia and macrophages in a superoxide dismutase-1 G93A mouse model of ALS.
[Proceedings Of The National Academy Of Sciences Of The United States Of America] |
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| Researchers showed that ubiquitin c-terminal hydrolase l-1 (UCHL1) promoted neural stem cell activation by clearing protein aggregates through ubiquitin-proteasome approach.
[Cell Death & Disease] |
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| The authors indicated that neural progenitor cell-derived extracellular vesicles were protective against the ischemic cascade activated by stroke.
[Cell Death Discovery] |
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| Using a juvenile mouse model of measles virus infection, where only mature neurons in the brain are infected, scientists defined the effects of the antiviral immune response on neural stem cells from juvenile to adult stages of life.
[Journal of Neurochemistry] |
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| The authors investigated the effects of changing CD97 levels and its function on primary patient-derived glioblastoma stem cells in vitro and in vivo.
[Journal of Biological Chemistry] |
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| Scientists found that increased TRIB1 gene expression was associated with worse overall survival of glioblastoma patients across multiple cohorts.
[Scientific Reports] |
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| Investigators explored the effect of SPOPL on the proliferation, self-renewal, and differentiation ability of glioma stem cells in vivo and in vitro.
[Journal of Neuro-Oncology] |
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| Researchers showed that human brain organoids provide a detailed and artifact-free window into neuromodulation-evoked electrophysiological effects.
[Heliyon] |
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| Scientists focus on the impairments of the insulin and insulin-like growth factor 1 (IGF1) signaling cascade in the context of neurodevelopmental and neuropsychiatric disorders, based on evidence from human neuronal cell models.
[Neuroscience & Biobehavioral Reviews] |
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| The health of our fat cells may influence the health of other organs and obesity researcher Akhila Rajan, PhD, has received a McKnight Foundation award to map that link.
[Fred Hutchinson Cancer Center] |
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| Flinders University researchers were awarded almost $4.5 million in four successful Future Fellowships by the Australian Research Council, including Dr. Cedric Bard and their research utilizing human brain organoid models.
[Flinders University] |
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| September 4 – 7, 2023
Surrey, England, United Kingdom |
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| | University of Florida – Gainesville, Florida, United States |
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| | University of California, Berkeley – Berkeley, California, United States |
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| | University of Calgary – St. Albert, Alberta, Canada |
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| | NICHD – Bethesda, Maryland, United States |
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| | University of Cincinnati – Cincinnati, Ohio, United States |
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