| Vol. 17.32 – 16 August, 2023 |
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| Researchers analyzed the intratumoral blood-brain-tumor barrier heterogeneity in human glioblastoma and characterized two genetically engineered models in female mice that recapitulated two important glioma phenotypes. [Nature Communications] |
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PUBLICATIONSRanked by the impact factor of the journal |
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| The authors identified the therapeutic target NF-E2-related factor 2 (Nrf2) that modulated neuroinflammation-triggered reactive astrocyte conversion. [Proceedings Of The National Academy Of Sciences Of The United States Of America] |
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| Investigators demonstrated the functional importance of cell adhesion molecule-downregulated oncogene (Cdon) in motor neuron function and nerve repair. [Journal Of Cachexia Sarcopenia And Muscle] |
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| Scientists investigated the distribution and functional relevance of fibroblast growth factor receptor 1 (FGFR1) and FGFR2 in human glioblastoma xenograft models. [Cancer Letters] |
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| Researchers showed that US28 increased the malignancy of U251 glioblastoma cells by enhancing signaling mediated by sphingosine-1-phosphate (S1P), a bioactive lipid that stimulated oncogenic pathways in glioblastoma. [Science Signaling] |
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| Investigators employed Neuronal Differentiation 4 (NeuroD4), a crucial transcription factor in neuronal development, to reprogram glioblastoma cells into neuron-like cells. [Cell Death Discovery] |
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| Researchers demonstrated that a new class of asymmetric, charge balanced waveforms were effective at directing retinal ganglion cell axon growth, in vitro, without compromising cell viability. [Scientific Reports] |
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| The authors investigated the biological functions of stromal interactive molecule 2 (STIM2) and its related mechanisms in cerebral ischemia/reperfusion injury progression. [Molecular Biotechnology] |
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| Scientists defined the role of polo-like kinase 3 (PLK3)-dependent proneural–mesenchymal transition in glioblastoma therapy. [Molecular Biology Reports] |
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| The authors explore the exosome–glioblastoma (GBM) interlink, the clinical impact of exosomes on GBM biomarkers, the therapeutics signature of exosomes in GBM, exosome-based research challenges, and future directions in GBM. [ACS Biomaterials Science & Engineering] |
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| The Robert H. Lurie Comprehensive Cancer Center of Northwestern University has received a renewed $10.8 million Specialized Program of Research Excellence (SPORE) grant to advance translational research and improve outcomes for patients with brain cancer. [Northwestern University] |
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| October 1 – 4, 2023 Whistler, British Columbia, Canada |
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| Van Andel Institute – Grand Rapids, Michigan, United States |
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| Creative Biolabs – New York, New York, United States |
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| Center for Excellence in Molecular Cell Science – Shanghai, China |
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| Weill Cornell – New York, New York, United States |
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| Cedars-Sinai – Los Angeles, California, United States |
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