 | | Vol. 18.00 – 10 January, 2024 |
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| Researchers designed a high-content imaging assay based on morphological and functional readouts in human pluripotent stem cell-derived cortical neurons which identified multiple compounds that drive neuronal maturation.
[Nature Biotechnology] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Using in vivo two-photon imaging in mice, the authors showed that microglia enhanced neuronal activity after the cessation of isoflurane anesthesia.
[Nature Neuroscience] |
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| Scientists reported a human organoid model capable of developing the complex cellular diversity of the fetal cerebellum, including a human-specific rhombic lip progenitor population that have never been generated in vitro prior to this study.
[Cell Stem Cell] |
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| Researchers identified 410 survival-associated IP genes in 33 cancer types using a machine-learning approach.
[EMBO Journal] |
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| Scientists used in vivo fiber photometry and optogenetics to record from and manipulate ventral pallidum→ventral tegmental area in rats performing a discriminative stimulus task to determine the role these neurons play in invigoration and reinforcement by reward cues.
[Cell Reports] |
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| Investigators established neuronal cell types and generated spinal cord organoids derived from C9orf72 knockdown human iPSCs to model amyotrophic lateral sclerosis disease and screen the unrevealed phenotype.
[Molecular Neurobiology] |
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| Scientists sought to shed light on the repercussions of prolonged exposure to heated tobacco products on the central nervous system, employing a mouse model mimicking prodromal Alzheimer’s disease.
[Scientific Reports] |
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| Researchers monitored the long- and short-term effects of mammalian target of rapamycin (mTOR) signaling regulation on cerebral organoid growth, differentiation, and function using an mTOR inhibitor and an mTOR activator.
[Tissue Engineering And Regenerative Medicine] |
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| Scientists investigated the ability of M2 muscarinic acetylcholine receptor to modulate cell migration in two different glioblastoma cell lines: U87 and U251.
[Neurochemistry International] |
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| The authors review the ability of ARHGAP11B to amplify basal progenitors and to expand a primate neocortex and discuss the contribution of ARHGAP11B to neocortex expansion during human evolution.
[Journal of Comparative Neurology] |
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| 4D Molecular Therapeutics announced a strategic partnership focused on advancing new AAV-based gene-editing therapies for central nervous system (CNS) diseases with high unmet medical needs in both rare and common disease populations.
[4D Molecular Therapeutics] |
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| February 11 – 16, 2024
Galveston, Texas, United States |
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| | University of Florida – Gainesville, Florida, United States |
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| | Human Technopole – Milan, Italy |
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| | University of Michigan – Ann Arbor, Michigan, United States |
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| | The Hong Kong University of Science and Technology – Guangzhou, China |
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| | University of Texas Health Science Center at San Antonio – San Antonio, Texas, United States |
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