Neural Cell News Volume 18.08 | Mar 6 2023

    0
    5







    2024-03-06 | NCN 18.08


    Neural Cell News by STEMCELL Technologies
    Vol. 18.08 – 6 March, 2024
    TOP STORY

    Multisensory Gamma Stimulation Promotes Glymphatic Clearance of Amyloid

    Researchers showed that multisensory gamma stimulation promoted the influx of cerebrospinal fluid and the efflux of interstitial fluid in the cortex of the 5XFAD mouse model of Alzheimer’s disease.
    [Nature]

    Full ArticlePress Release
    View tips on how to plan ahead and get the most out of your time in the lab.
    PUBLICATIONSRanked by the impact factor of the journal

    Neuronal Dynamics Direct Cerebrospinal Fluid Perfusion and Brain Clearance

    The authors demonstrated that neural networks synchronized individual action potentials to create large-amplitude, rhythmic, and self-perpetuating ionic waves in the interstitial fluid of the brain.
    [Nature]

    AbstractPress Release

    NOVA1 Acts as an Oncogenic RNA-Binding Protein to Regulate Cholesterol Homeostasis in Human Glioblastoma Cells

    Scientists found that NOVA1 acted as an oncogenic factor in a glioblastoma multiforme cell line established from a patient.
    [Proceedings Of The National Academy Of Sciences Of The United States Of America]

    Abstract

    Metabolic Rescue of α-Synuclein-Induced Neurodegeneration through Propionate Supplementation and Intestine-Neuron Signaling in C. elegans

    Researchers found that the short-chain fatty acid propionate protected against α-synuclein-induced neuronal death and locomotion defects in a Caenorhabditis elegans model of Parkinson’s disease through bidirectional regulation between the intestine and neurons.
    [Cell Reports]

    Full ArticleGraphical Abstract

    Neural Conditional Ablation of the Protein Tyrosine Phosphatase Receptor Delta PTPRD Impairs Gliogenesis in the Developing Mouse Brain Cortex

    The authors developed a conditional knockout mouse model lacking phosphatase receptor delta (PTPRD) expression in telencephalon cells. They found that the lack of PTPRD in the mouse cortex reduces glial precursors, astrocytes, and oligodendrocytes.
    [Frontiers in Cell and Developmental Biology]

    Full Article

    Altered Hippocampal Neurogenesis in a Mouse Model of Autism Revealed by Genetic Polymorphisms and by Atypical Development of Newborn Neurons

    Investigators found coding non-synonymous single-nucleotide polymorphisms in 33 genes involved in the adult neurogenic process, as well as in 142 genes associated with the signature genetic profile of neural stem cells and neural progenitors.
    [Scientific Reports]

    Full Article

    Expression Patterns of Piezo1 in the Developing Mouse Forebrain

    Researchers conducted an RNAscope experiment to visualize the location of Piezo1 transcripts with embryonic neuronal/glial lineage cell markers.
    [Brain Structure & Function]

    Abstract
    Tools to isolate, culture, and assay cells. Click to explore.
    REVIEWS

    Mitochondrial Metabolism in Neural Stem Cells and Implications for Neurodevelopmental and Neurodegenerative Diseases

    Scientists analyze the physiology and pathology of neural development starting from the available in vitro and in vivo models and highlight the current knowledge concerning key mitochondrial pathways involved in this process.
    [Journal of Translational Medicine]

    Full Article
    INDUSTRY AND POLICY NEWS

    Computer Scientist Wins NSF CAREER Award to Advance Alzheimer’s Research Using AI

    Assistant professor Minghan Chen was recently awarded a five-year, $500,000 National Science Foundation (NSF) CAREER Award for her research project entitled: “Towards a Living Neuron Twin for Improving Human Cognitive Health”.
    [Wake Forest University]

    Press Release
    FEATURED EVENT

    2nd International Conference on Cancer and Oncology Research

    April 15 – 16, 2024
    London, England, United Kingdom

    > See All Events

    JOB OPPORTUNITIES

    Faculty Positions – Neurobiology

    Westlake University – Zhejiang, China

    PhD Position – Neurodevelopmental Disorders

    VIB – Ghent, Belgium

    Group Leader Positions – Genetics, Molecular, and Cellular Biology

    The Institute of Genetics, Molecular and Cellular Biology – Strasbourg-Ville, France

    Research & Development Specialist – Bio Medical Image Analysis

    Luxembourg Centre for Systems Biomedicine – Esch-sur-Alzette, Luxembourg

    Post Doctoral Scholar – Neurology

    The Lundquist Institute – Torrance, California, United States

    > See All Jobs

    Submit an article, publication, job or event
    Brought to you by
    stemcell-logo-for newsletter-2