 | | Vol. 18.13 – 10 April, 2024 |
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| The authors showed that glioblastoma stem cells reprogrammed the epigenetic landscape by producing substantial amounts of phosphocreatine.
[Cancer Discovery] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| To monitor how depolarization impacted local dendritic biology, researchers employed a dendritically targeted proximity labeling approach followed by crosslinking immunoprecipitation, ribosome profiling, and mass spectrometry.
[Nature Neuroscience] |
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| To understand the mechanistic significance of inter-regional projections on development of neural circuits, the authors investigated an in vitro neural tissue model for inter-regional connections, in which two cerebral organoids were connected with a bundle of reciprocally extended axons.
[Nature Communications] |
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| Scientists identified that IFI35, a transcriptional regulatory factor, played both cell-intrinsic and cell-extrinsic roles in maintaining glioma stem cells and the immunosuppressive tumor microenviroment.
[Cell Death & Differentiation] |
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| Investigators found two distinct pools of neural precursors based on Sara endosome inheritance and spindle-microtubule enrichment. Symmetric or asymmetric levels of spindle-microtubules drove differently Sara endosomes inheritance and predicted neural precursor lineage.
[Communications Biology] |
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| Researchers investigated the earliest molecular pathology of spinocerebellar ataxia type 1 (SCA1), a rare familial neurodegenerative disease that primarily induces death and dysfunction of cerebellum Purkinje cells.
[Communications Biology] |
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| The authors investigated how modulating autophagy affected the exosomal release of amyloid and tau proteins in animal models of Alzheimer’s disease.
[Inflammopharmacology] |
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| Investigators highlight how recent methodological innovations — including single-cell transcriptomics, CRISPR-based screens, and human cell-based models of disease — are enabling new breakthroughs in our understanding of selective vulnerability.
[Nature Reviews Neuroscience] |
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| Scientists critically discuss immunological mechanisms of central neurodegeneration and propose potential strategies to correct neurodegeneration-associated immunological dysfunction with therapeutic purposes.
[Cell Discovery] |
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| Essential Pharma announced that it has completed the acquisition of the entire issued share capital of Renaissance Pharma Ltd. Renaissance Pharma is a clinical stage pharmaceutical company focused on the development of life changing therapies in pediatric rare disease.
[Essential Pharma] |
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| St. Bonaventure University senior Nishtha Tripathi of Austin, Texas, was among 31 undergraduate students nationwide who were accepted into the competitive American Society for Biochemistry and Molecular Biology Honor Society for 2024.
[St Bonaventure University] |
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| May 20, 2024
New York, New York, United States & Online |
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| | University of Michigan – Ann Arbor, Michigan, United States |
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| | The University of Tennessee Health Science Center – Memphis, Tennessee, United States |
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| | Leibniz Institute for Neurobiology – Magdeburg, Germany |
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| | NYU Langone Health – New York City, New York, United States |
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