| REVIEWS | Newborn Cortical Neurons: Only for Neonates? The authors review evidence of the existence, origin, migration, and integration of neurons into the adult and neonatal cerebral cortex. They emphasized that neurogenesis occurs in the neonatal cortex and that neural stem cells are present into adulthood; it is possible that these progenitors are dormant, but they may be reactivated, for example, following injury. [Trends Neurosci] Abstract Role of Neural Precursor Cells in Promoting Repair following Stroke Investigators discuss the current state of the stem cell-based approaches with a focus on endogenous repair to treat the stroke injured brain. [Acta Pharmacol Sin] Abstract |
| INDUSTRY NEWS | FDA Approves Neuralstem to Treat Second Cohort in NSI-189 Phase Ib Trial in Major Depressive Disorder Neuralstem, Inc. announced that it has begun dosing the second cohort of patients in its ongoing phase Ib to test the safety of NSI-189 in the treatment of major depressive disorder (MDD). NSI-189 is a proprietary new chemical entity that stimulates new neuron growth in the hippocampus, a region of the brain believed to be implicated in MDD, as well as other diseases and conditions such as: chronic traumatic encephalopathy, Alzheimer’s disease, and post-traumatic stress disorder. [Neuralstem, Inc.] Press Release UC Irvine Opens Clinical Trial of Novel Treatment for Brain Cancer UC Irvine doctors are enrolling patients with the deadly brain tumor glioblastoma multiforme in a clinical trial of a vaccine that may prevent the cancer’s return or spread after surgery. [University of California, Irvine] Press Release StemCells, Inc. Launches Four New Human Neural Stem Cell Kits Under SC Proven(R) Brand StemCells, Inc. announced the launch of four new SC Proven human neural stem cell (NSC) kits for use in neuroscience research. Each kit will contain high purity, multipotent NSCs derived from a different area of the human central nervous system, and will provide researchers with a reproducible and scalable serum-free platform with which to perform a broad range of assays. [StemCells, Inc.] Press Release Intellect Neurosciences Files Lawsuit against Pharmaceutical Licensee for Non Payment of $2 Million Milestone Intellect Neurosciences, Inc. announced it has filed a lawsuit in the New York State Supreme Court against a top tier global pharmaceutical company for breach of the licensing agreement between the parties. [Intellect Neurosciences, Inc.] Press Release |
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