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| Researchers report the generation of arcuate organoids from human iPSCs to model the development of the human hypothalamic arcuate nucleus.
[Cell Stem Cell] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| The authors adapted a mechanical sample processing method to generate lung cancer organoids from surgically resected and biopsy tumor tissues.
[Nature Communications] |
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| Investigators reported that epithelial ductal elongation within human mammary organoid branches relied on the non-linear and plastic mechanical response of the surrounding collagen.
[Nature Communications] |
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| Researchers demonstrated that their mini-bioreactors could stably maintain the rotational speed of organoids during long-term culture, and enhance neural differentiation and uniformity of organoids.
[Lab On A Chip] |
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| Investigators used human embryonic stem cell-derived cortical organoids to investigate whether SARS-CoV-2 could infect brain tissue in vitro and found that cortical organoids could be infected at low viral titers and within six hours.
[Stem Cell Reports] |
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| Investigators report on efforts to generate patient‐derived organoids from a cohort of 81 prostate cancer specimens with diverse pathological and clinical features. They comprehensively analyzed histological features of each enrolled sample and correlated it with organoid growth patterns.
[Journal of Pathology] |
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| Scientists compared the replicative fitness and human respiratory syncytial virus (HRSV)-induced innate cytokine responses of HRSV-A and HRSV-B strains in disease-relevant cell culture models.
[mSphere] |
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| Using a novel screening method, investigators identified novel transcription factors that regulated the intestinal stem cell fate upon endoplasmic reticulum stress.
[Scientific Reports] |
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| The authors found that LINGO3 was broadly expressed on human enterocytes and sparsely on discrete cells within the crypt niche, that contained intestinal stem cells.
[Scandinavian Journal of Gastroenterology] |
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| To promote the standardization and validation of hepatic, pancreatic, and biliary organoids, scientists propose guidelines for establishing, characterizing, and benchmarking future systems.
[Cell Stem Cell] |
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| Investigators review the state-of-the-art of preclinical in vitro models in osteoarthritis and outline how the different preclinical systems may be valid tools in regenerative medicine, describing their pros and cons.
[Journal of Clinical Medicine] |
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| MIMEDX Group, Inc. announced a collaborative agreement with the Wake Forest Institute for Regenerative Medicine to develop and advance scientific evidence in support of safe and effective clinical therapies. The partnership reflects a shared vision to advance regenerative science and innovative biologics that restore quality of life for patients, and is geared to further understanding product mechanisms of action and potential therapeutic targets.
[MIMEDX Group, Inc.] |
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| Accelerated Biosciences announced new data that further demonstrates statistically significant cytolysis with iPSc-derived natural killer cells programmed from its ethically sourced hTSCs.
[Accelerated Biosciences (BusinessWire, Inc.)] |
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| September 28 -30, 2021
Virtual |
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| | UMB School of Medicine – Baltimore, Maryland , United States |
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| | Case Western Reserve University – Cleveland, Ohio, United States |
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| | Karolinska Institutet – Solna, Sweden |
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| | Elsevier – Cambridge, Massachusetts, United States |
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| | Stanford University – Stanford, California, United States |
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