 | | Vol. 3.04 – 3 February, 2022 |
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| Investigators generated a human model for tuberous sclerosis complex (TSC) by growing cerebral organoids from patients who carried mutations in TSC2.
[Science] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| The authors used multiple conditional deletion models to identify a role for IL-17A in secretory epithelial cell differentiation in the gut.
[Immunity] |
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| Investigators showed strong, graded, repetitive, and wavelength-specific light-evoked responses from retinal organoid cones.
[Cell Stem Cell] |
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| Individual cystic fibrosis transmembrane conductance regulator function was defined by forskolin-induced swelling, measured as the relative size increase of intestinal organoids after stimulation with 0.8 µM forskolin, quantified as area under the curve.
[European Respiratory Journal] |
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| By elucidating the in vivo molecular features of the renal stromal lineage at a single-cell resolution level, researchers established an in vitro induction protocol for stromal progenitors from mouse PSCs.
[Nature Communications] |
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| Researchers investigated the dynamics of basement membrane assembly in human PSC-derived kidney organoids.
[eLife] |
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| Scientists showed that in-trans paired nicking allowed for fast, highly efficient, and indel-free fluorescent gene tagging in human normal and cancer organoids.
[PLoS Biology] |
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| Investigators developed a method for live-cell imaging of microbial infection dynamics on human adult stem cell-derived intestinal epithelial cell layers.
[mBio] |
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| Using iPSC derived kidney organoids, SARS-CoV-1, SARS-CoV-2 and MERS-CoV tropism, defined by the paired expression of a host receptor and protease, was identified primarily amongst proximal tubule cells.
[iScience] |
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| The recent progress of organoids and organs-on-chips for virology research is summarized and their utility in meeting the COVID-19 pandemic is highlighted.
[Advanced Science] |
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| Novo Nordisk Foundation will invest up to $343 million over a ten-year period to establish an international research center focused on stem cell medicine.
[BNovo Nordisk Foundation (Process International)] |
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| The ISS will include an experiment by five students from the Luxembourg Center of System Biomedicine at Belval, who have been growing so-called “organoids”, mini brains that will be able to grow in micro gravity and thus help advance research in the fight against Parkinson’s disease.
[RTL Luxembourg] |
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| | Knight Cancer Institute – Portland, Oregon, United States |
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| | Harvard Medical School – Boston, Massachusetts, United States |
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| | King’s College London- London, England, United Kingdom |
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| | University of Nottingham – Nottingham, England, United Kingdom |
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| | Stanford University – Stanford, California, United States |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
