 | | Vol. 3.06 – 17 February, 2022 |
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| Volumetric bioprinting via optical tomography shaped organoid-laden gelatin hydrogels into complex centimeter-scale 3D structures in under 20 seconds.
[Advanced Materials] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| In this proof-of-concept study, the authors successfully established organoids from seven chordoma tumor samples obtained from five patients presenting with tumors in different sites and stages of disease.
[Science Advances] |
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| Scientists showed that IL-18 was a bona fide IL-22-regulated gate keeper for intestinal epithelial barrier.
[Nature Communications] |
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| Investigators devised a straightforward bioengineered neural organoid culture approach entailing transcription factor–driven direct differentiation of neurons and astrocytes from human PSC combined with genetically encoded tools for dual cell-selective activation.
[Journal of Cell Biology] |
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| Researchers described suspension culture as a simple, low-maintenance method for culturing human intestinal organoids and for promoting in vitro differentiation of an organized serosal mesothelial layer that was similar to primary human intestinal serosal mesothelium based on single-cell RNA sequencing and histological analysis.
[Cell Reports] |
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| The authors investigated the role of the tumor stem cell marker DCLK1 in epithelial growth factor receptor-tyrosine kinase inhibitor resistance of lung adenocarcinoma.
[Cancer Letters] |
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| Scientists reported a noninvasive technique to generate human nose organoids as an alternative to biopsy-derived organoids.
[mBio] |
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| Retinal organoids produced from rhesus monkey iPSCs using established protocols differentiated through the stages of organoid development faster than those derived from human stem cells.
[Cell Proliferation] |
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| Scientists addressed the relevance of 3D organoid technology to investigate the biological effects of cold atmospheric plasma on normal epithelial stem cells and tumor cells isolated from mouse small intestine.
[Cell Death Discovery] |
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| Investigators review existing data on the electrophysiological properties of neurons in human cortical organoids, as well as recent advances in the complexity of cortical organoid modeling that have led to improvements in functional maturation at single neuron and neuronal network levels.
[Frontiers in Molecular Neuroscience] |
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| The authors discuss applications to address the currently unmet need of developing physiologically relevant in vitro and ex vivo models of ovarian cancer for fundamental discovery science and personalized medicine approaches.
[Frontiers in Bioengineering and Biotechnology] |
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| Priscilla Hwang, Ph.D., an assistant professor in the Department of Biomedical Engineering in the VCU College of Engineering, has received a Faculty Early Career Development Award from the National Science Foundation for 2022.
[Viriginia Commonwealth University] |
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| April 3 – 6, 2022
Warwick, England, United Kingdom |
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| | University Of Wisconsin–Madison – Madison, Wisconsin, United States |
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| | Francis Crick Institute – London, England, United Kingdom |
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| | IRB Barcelona – Barcelona, Spain |
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| | King’s College London- London, England, United Kingdom |
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| | Harvard Medical School – Boston, Massachusetts, United States |
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