| Vol. 3.28 – 21 July, 2022 |
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| A luminescent approach to detect hepatic cell fate marker albumin in vitro and living cell labeling with upconversion nanoparticles, which were conjugated with antibody and rose bengal hexanoic acid was reported. [Advanced Science] |
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PUBLICATIONSRanked by the impact factor of the journal |
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| Using primary human prostate organoids, investigators evaluated whether inhibiting an acK13-HOXB13 target, ACK1, with a selective inhibitor (R)-9b was superior to androgen receptor antagonists in inhibiting castration resistant prostate cancer growth. [Clinical Cancer Research] |
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| Scientists developed organoids from human fetal fallopian tubes and uteri and compared them with their adult counterparts. [Proceedings of the National Academy of Sciences of the United States of America] |
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| Patient-derived organoid models demonstrated that KS10076 efficiently represses cancer cells with active KRAS, and fluorouracil resistance, which suggested clinical advantages. [Cell Reports] |
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| Using the gut tube-derived organoids, the authors found that the cell fate of the foregut and hindgut could be switched by the regional niche factors, including fibroblast growth factors and retinoic acid. [Cell Reports] |
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| Researchers reported one unique case of synchronous intestinal cancer with tumors occurring along the entire bowel tract, including the small intestine. [NPJ Genomic Medicine] |
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| Scientists determined temozolomide-resistant GBM cell was the most sensitive to the tested compounds, and found hemsleyaoside N displayed the best antineoplastic potency. [Bioorganic Chemistry] |
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| The authors used endoscopic ultrasound-guided fine-needle aspiration to collect pancreatic cancer tissues from patients with advanced pancreatic cancer to create organoids, and evaluated their utility in pancreatic cancer research. [Gut and Liver] |
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| Investigators established a framework for cell culture, formation of tumor spheroids, fluorescence labeling, and imaging of fixed or live cells at various magnifications directly in the chip together with data analysis and interpretation. [Cell Reports Methods] |
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| Scientists highlight novel advances in organoid biology with a focus on how organoid technology has generated a better understanding of human-specific processes in development and disease. [Cell] |
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| Governor Gretchen Whitmer used her veto pen on the state’s education budget Thursday to strike funding for pregnancy centers and stem cell research, saying that wording within the bill tried to “create a gag rule” concerning abortion. [Advance Local Media LLC] |
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| Aug 7 – 12, 2022 Steamboat Springs, Colorado, United States |
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| Ohio State University Wexner Medical Center – Columbus, Ohio, United States |
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| Weill Cornell Medical College – New York, New York, United States |
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| Lehigh University – Bethlehem, Pennsylvania, Untied States |
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| The Chinese University of Hong Kong – Hong Kong, China |
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| Baylor College of Medicine – Houston, Texas, United States |
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