 | | Vol. 3.49 – 15 December, 2022 |
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| Researchers identified an alveolar-fated epithelial progenitor in human fetal lungs, which they grew as self-organizing organoids that modeled key aspects of cell lineage commitment.
[Cell Stem Cell] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists described the establishment of nasopharyngeal and bronchial organoids from healthy individuals and chronic obstructive pulmonary disease that recapitulated the disease at the individual level.
[Nature Communications] |
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| High-speed scanning ion conductance microscope as a powerful tool was utilized to simultaneously reveal morphologies and local elastic modulus of basal surface of genotype-defined metastatic intestinal organoids.
[Small] |
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| Researchers revealed that the CXCR2 ligand granulocyte chemotactic protein 2 was expressed, during embryonic development, within the prospective permanent articular cartilage, but not in the epiphyseal cartilage destined to be replaced by bone.
[EMBO Molecular Medicine] |
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| The authors generated a dual-fluorescence model to track and analyze dental cells from embryonic to postnatal stages, in which Pitx2+ epithelium and Msx1+ mesenchyme were sufficient for tooth reconstitution.
[Cell Reports] |
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| Investigators summarize the recent progress of novel approaches to engineering oral and maxillofacial organoids.
[Scientific Data] |
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| Researchers loaded liquid chromatography column housings with induced pluripotent stem cell derived liver organoids and coupled the “organ-in-a-column” units on-line with liquid chromatography-mass spectrometry.
[Analytical Chemistry] |
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| After ectopic expression and depletion experiments in pancreatic cancer cells, oncogenic phenotypes of pancreatic cancer cells were tested by MTS assay, Transwell assay, and flow cytometry.
[Clinical and Translational Oncology] |
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| Scientists reported a system supported culturing of kidney organoids, which presented nephron structures. They showed that organoids cultured on chip showed increased maturation of endothelial populations based on a colocalization analysis of endothelial markers.
[Scientific Reports] |
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| Investigators review the current methods used to generate microglia-containing human brain organoids (MC-HBOs) and provide opinions on the use of MC-HBOs for disease modeling and functional studies.
[Molecular Psychiatry] |
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| The authors summarize the recent progress of novel approaches to engineering oral and maxillofacial organoids. They introduce the necessary components and their roles in forming oral and maxillofacial organoids.
[iScience] |
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| Building on a strong track record of collaboration, the Biotechnology and Biological Sciences Research Council and the NC3Rs have committed £3.7M through a joint call to develop the next generation of non-animal technologies.
[NC3Rs] |
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| March 6 – 8, 2023
Paris, France |
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| | | Rutgers Biomedical and Health Sciences – Newark, New Jersey, United States |
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| | University of California Irvine – Irvine, California, United States |
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| | Baylor College of Medicine – Houston, Texas, United States |
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| | Center for Nanomedicine and Tissue Engineering – Milan, Italy |
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| | Lund University – Lund, Sweden |
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