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| Researchers presented a pipeline to generate bioprinted tumor organoids linked to label-free, time-resolved imaging via high-speed live cell interferometry and machine learning-based quantitation of individual organoids.
[Nature Communications] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| To facilitate drug discovery combating immunosuppressive pancreatic ductal adenocarcinoma, a high-throughput drug screen platform was established with the newly developed T cell-incorporated pancreatic tumor organoid model.
[Advanced Science] |
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| Researchers knocked down immune checkpoints and immunosuppressive molecular receptors in CAR-T cells by constructing two clusters of small hairpin RNAs and evaluated the engineered CAR-T cells for antitumor activity both in vitro, using tumor cell lines and cholangiocarcinoma organoid models, and in vivo.
[Cancer Communications] |
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| Investigators generated brain organoids using engineered extracellular matrix comprised of human fibrillar fibronectin supported by a highly porous polymer scaffold.
[Annals Of Clinical And Translational Neurology] |
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| Hepatocytes and hepatic stellate cells exhibited more pronounced phenotypic arrangements when cocultured with laminin-511 and 521 modified chitosan microparticles.
[Biotechnology And Bioengineering] |
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| Scientists presented a proof-of-concept study for the integration of biofunctionalized gold nanoribbons with hiPSC-derived isogenic cardiac organoids to enhance tissue function and maturation.
[Rsc Advances] |
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| 3D printing was used to fabricate a custom-designed platform box for mounting the chosen smallest footprint components. A demonstrator system was realized for lung-on-a-chip experiments.
[Biomedical Microdevices] |
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| The authors generated brain/cerebral organoids from human iPSCs to study the radiosensitivity of human brain cells, including neurons, astrocytes, and oligodendrocytes.
[PLOS One] |
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| Investigators generate midbrain dopaminergic organoids from induced pluripotent stem cells from healthy and Parkinson’s Disease (PD) donors and assess them as a human PD model using single-cell RNAseq.
[Neuroscience Research] |
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| The authors review the events of early retinal development both in animal embryos and human retinal organoids (hROs) studies, and summarize the application prospect, challenges, and cutting-edge techniques of hROs for uncovering mechanisms of retinal development and related developmental disorder.
[Stem Cell Reviews And Reports] |
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| Scientists provide a comprehensive view of the available models for neuroendocrine prostate cancer (NEPC) detailing their strengths and limitations, and describe novel approaches to expand the repertoire of preclinical models to better study, prevent, or reverse NEPC.
[Current Protocols] |
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| The authors summarize the recent research in stem cells, genetic modifications, and organoids as a potential for treatment of Huntington’s disease.
[Brain Research Bulletin] |
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| University of California, Riverside (UCR) gains $2.9 million dollars from the California Institute for Regenerative Medicine for the Research Training and Mentorship Program Inspire Diverse Undergraduates toward Regenerative Medicine Careers, otherwise known as RAMP.
[University of California, Riverside (The Highlander)] |
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| The Council of the European Union has adopted conclusions on the ‘high quality, transparent, open, trustworthy and equitable scholarly publishing’, in which it calls for immediate and unrestricted open access in publishing research involving public funds.
[Council of the European Union] |
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| July 17 – 20, 2023
Burlington, Vermont, United States |
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| | Malm̦ University РMalm̦, Sweden |
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| | Human Technopole – Milan, Italy |
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| | National Institute of Allergy and Infectious Diseases – Hamilton, Montana, United States |
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| | Centre for Oncology and Immunology – Hong Kong, Hong Kong |
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| | Center for Disease Neurogenomics at the Icahn School of Medicine – Manhattan, New York, United States |
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