| Vol. 4.27 – 13 July, 2023 |
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| To solve challenges surrounding insufficient 3D resolution in the 3D reconstruction of living brain tissue, scientists developed an integrated optical/machine-learning technology, LIONESS, live information-optimized nanoscopy enabling saturated segmentation. [Nature Methods] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators developed a robust, reliable methodology for generating placenta villi organoids from early, late, or diseased pregnancies using air–liquid surface culture. [Advanced Science] |
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| Using mouse fetal and adult small intestinal organoids, researchers uncovered transcriptional differences between the fetal and adult state and identified rare adult-like cells present in fetal organoids. [Science Advances] |
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| Scientists produced embedded, bioprinted breast cancer cells and tumor organoid models using low concentration collagen I based bioinks. [Advanced Healthcare Materials] |
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| Investigators found that sumoylation promoted the interaction of SnoN with the epigenetic regulators histone deacetylase 1 (HDAC1) and histone acetylase p300 in epithelial cells. [Cell Death & Disease] |
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| Scientists found that α7nAChR, α7 nicotinic acetylcholine receptor, coded by Chrna7, was expressed on AT2 cells and was upregulated in response to LPS-induced acute lung injury. [JCI Insight] |
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| Researchers identified a bioactive peptide domain of type V collagen, WWASKS, through bioinformatic analysis of decellularized pancreatic extracellular matrix-derived collagens. [Journal Of Tissue Engineering] |
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| Intestinal organoids were used as an in vitro model to analyze the effects of four (epi)catechins on the development of the intestinal epithelial structure. [Food & Function] |
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| The authors presented an optimized protocol that allows high take-rate, and simultaneous propagation of patient-derived organoids and matching cancer-associated fibroblasts, from primary and metastatic hormone receptor-positive breast cancers. [Journal Of Biological Chemistry] |
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| Researchers presented the OrganoidChip, a microfluidic imaging platform that incorporates a unique design to immobilize organoids for endpoint, fast imaging. [Scientific Reports] |
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| The authors focus on how 3D printing technology can enhance the drug discovery process by automating tissue production that enables high-throughput screening of potential drug candidates. [Expert Opinion on Drug Discovery] |
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| Britain and the EU have reportedly agreed on a draft deal that would see the UK rejoin the bloc’s Horizon Europe science program – amid warnings that being outside is “damaging” British science. [INDEPENDENT] |
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| August 3, 2023 New York, New York, United States |
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| Centre for Oncology and Immunology – Hong Kong, Hong Kong |
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| University of Galway – Galway, Ireland |
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| Albert Einstein College of Medicine – New York, New York, United States |
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| Institute of Biology Valrose – Nice, France |
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| ForÂschungsÂzentrum Jülich – Jülich, Germany |
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