 | | Vol. 4.31 – 10 August, 2023 |
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| Investigators reported on fully synthetic hydrogels based on DNA libraries that self-assembled with ultrahigh-molecular-weight polymers, forming a dynamic DNA-crosslinked matrix.
[Nature Nanotechnology] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists reported the generation of multi-chambered self-paced vascularized human cardiac organoids formed under anisotropic stress and their applicability to the study of cardiac arrhythmia.
[Nature Biomedical Engineering] |
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| Researchers showed cardiac organoids engineered with electrically conductive silicon nanowires significantly enhanced the therapeutic efficacy of hPSC-derived cardiomyocytes to treat infarcted hearts.
[Science Advances] |
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| The authors generated iPSC-derived airway organoids (AOs) that resembled the human native airway. They subjected iPSC-AOs to SARS-CoV-2 infection and investigated the treatment effect of lipid modifiers statin drugs.
[Journal of Advanced Research] |
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| To investigate the effects of macrophage stimulation on gemcitabine resistance, co-cultures were set up using patient-derived organoids from three pancreatic adenocarcinoma patients with macrophages.
[Journal of Experimental & Clinical Cancer Research] |
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| Scientists applied sci-Plex, a single-cell combinatorial indexing-based RNA sequencing multiplexing method to retinal organoids.
[Cell Reports Methods] |
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| The authors investigated which entry route SARS-CoV-2 Omicron takes in relevant cell models of the human airway and intestine.
[Journal of Virology] |
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| Investigators analyzed the gene expression characteristics of neuronal organoids containing immature human retinal cells under low-dose radiation and predicted their changes.
[Scientific Reports] |
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| Researchers reported a long-awaited differential non-syndromic retinitis pigmentosa and Usher syndrome phenotype in three human disease-specific models: fibroblasts, iPSCs, and mature iPSC-derived retinal organoids.
[HGG Advances] |
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| The authors summarize the current understanding of potential mechanisms that drive SARS-CoV-2-induced cardiac dysfunction based on in vitro studies.
[Bioengineering & Translational Medicine] |
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| Scientists focus on recent advances in the application of organoids in cancer research and discuss the opportunities and challenges facing organoid research.
[Experimental Hematology & Oncology] |
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| Early-career researchers who work in labs operated by the US National Institutes of Health (NIH) have hit a roadblock on their way to unionizing.
[Science Insider] |
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| October 22 – 25, 2023
Salt Lake City, Utah, United States |
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| | University of Giessen – Giessen, Germany |
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| | Goethe University Frankfurt – Frankfurt, Germany |
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| | Friedrich Miescher Institute for Biomedical Research – Basel, Switzerland |
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| | IRB Barcelona – Barcelona, Spain |
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| | Harvard Medical School – Boston, Massachusetts, United States |
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