 | | Vol. 4.32 – 17 August, 2023 |
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| The authors used melt electrospinning writing to generate tuneable grid scaffolds that could guide the self-organization of PSCs into patterned arrays of embryoid bodies.
[Advanced Materials] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Single cell transcriptome integration revealed that most proteome changes localized to podocytes, tubular, and stromal cells.
[Nature Communications] |
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| Scientists presented an in-depth single-cell atlas of in vitro multiculture systems on human primary airway epithelium derived from normal and diseased lungs of 27 individual donors.
[Nature Communications] |
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| Investigators presented an in-depth single-cell atlas of in vitro multiculture systems on human primary airway epithelium derived from normal and diseased lungs of 27 individual donors.
[Experimental & Molecular Medicine] |
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| To study lymphoepithelial interaction, researchers employed a novel ex vivo T cell/organoid co-culture model system.
[Frontiers in Immunology] |
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| The authors tested the differential filtration-based mitochondrial isolation protocol established by the McCully laboratory for use in cellular models but found whole cell contaminants in the mitochondrial isolate.
[Stem Cell Research & Therapy] |
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| Using optic vesicle organoids to model the onset of the eye field, researchers generated time-course transcriptomic data to identify dynamic gene expression programs that characterized this cellular-state transition.
[Development] |
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| Using hiPSCs, genome editing technology, and organoid technology, investigators generated uridine diphosphate glucuronosyltransferase (UGT) A1-knockout human iPSC hepatocyte-derived liver organoids as a model for UGT1A1-specific kinetics and toxicity evaluation.
[Molecular Therapy-Methods & Clinical Development] |
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| To study stem cell–derived islet organoids in an organ-on-chip platform, scientists developed a RPLC–MS/MS method allowing for simultaneous determination of insulin, somatostatin-14, and glucagon, with improved matrix robustness.
[ELECTROPHORESIS] |
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| The authors discuss the current use of patient-derived organoids in complex 3D in vitro models of the tumor microenvironment and highlight emerging directions in the development of these models.
[Advanced Healthcare Materials] |
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| Scientists propose developing a combinatorial approach that allows the integration of patient-derived iPSCs/organoids with 3D bioprinting and organ-on-a-chip technique as it would encompass the neuronal cells along with their niche.
[Cell and Tissue Research] |
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| India’s Parliament approved a new research funding agency aimed at boosting the nation’s scientific standing. But some analysts are skeptical that the Anusandhan National Research Foundation—which aims to inject some $6 billion into basic and applied research over 5 years—will have a major impact.
[Science Insider] |
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| November 7 – 8, 2023
London, England, United Kingdom |
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| | National University Singapore – Singapore, Singapore |
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| | Creative Biolabs – New York, New York, United States |
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| | University of Giessen – Giessen, Germany |
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| | Goethe University Frankfurt – Frankfurt, Germany |
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| | Max Planck Institute – Dresden, Germany |
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