 | | Vol. 4.46 – 23 November, 2023 |
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| Investigators presented a novel, multicellular liver organoid (LO) model using a co-culture system of macrophages and LOs differentiated from the same human PSCs.
[Hepatology] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| A drug sensitivity test was performed using patient-derived organoids from the patient tissue and the primary cancer characteristics of pateint-derived organoids were confirmed by pathological comparision with tissue slides.
[Journal Of Experimental & Clinical Cancer Research] |
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| Scientists presented a hybrid endometrial-derived hydrogel that combined the rigidity of PuraMatrix with the natural scaffold components and interactions of a decellularized porcine endometrial extracellular matrix hydrogel.
[Advanced Healthcare Materials] |
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| The authors demonstrated that embryoid bodies and various organoid models could be optimized by using the chroman 1, emricasan, polyamine, trans-ISRIB (CEPT) small molecule cocktail, a polypharmacology approach that ensured cytoprotection and cell survival.
[Biofabrication] |
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| Researchers developed a 3D printing pipeline for the fabrication of tailor-made culturing platforms for fluidically connected but spatially separated brain organoid array culture.
[Biofabrication] |
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| Using mESC-derived thyroid organoids, scientists developed a BrafV637E-inducible model able to recapitulate the features of papillary thyroid cancer in vitro.
[Oncogene] |
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| For the vascularization study, kidney organoids were generated from hiPSCs. Researchers overexpressed hypoxia-inducible factor-1 α (HIF-1α) via plasmid transfection or treated dimethyloxallyl glycine in kidney progenitor cells to detect the endothelium.
[Stem Cell Research & Therapy] |
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| Using trophoblast stem cells, trophoblast organoids, and primary cytotrophoblasts of early pregnancy, scientists showed that autocrine NOTCH3 signaling controlled human placental expansion and differentiation.
[Development] |
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| Investigators developed a human brain organoid technique that generated self-organizing, single-rosette cortical organoids with reproducible size and structure at early timepoints.
[Stem Cell Reports] |
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| Human intestinal organoids derived from PSCs or adult stem cell biopsies represent a powerful platform to study human development, drug testing, and disease modeling in vitro, and serve as a cell source for tissue regeneration and therapeutic advances in vivo.
[Advanced Materials] |
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| Scientists review recent advances in natural biomaterials-based glioblastoma organoid models, as in vitro experimental platforms to simulate glioblastoma tumor biology and response to tested drugs.
[International Journal of Biological Macromolecules] |
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| Artificial intelligence tools promise to help researchers digest scholarly literature in new ways, but technical and legal barriers may hinder widespread use.
[Science] |
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| February 14 – 18, 2024
Cancun, Mexico |
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| | Weill Cornell Medicine – New York City, New York, United States |
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| | Swammerdam Institute for Life Sciences – Amsterdam, Netherlands |
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| | Applied Stem Cell – Milpitas, California, United States |
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| | China Pharmaceutical University – Nanjing, Jiangsu, China |
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| | Baylor College of Medicine – Houston, Texas, United States |
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Cancer Stem Cell News
Cell Therapy News
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