 | | Vol. 4.49 – 14 December, 2023 |
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| Scientists demonstrated the ability to generate mineralizing dental epithelial organoids from adult dental epithelial stem cells isolated from mouse incisor tissues.
[International Journal of Oral Science] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers showed that heart organoids produced using a self-organization-driven developmental induction strategy were remarkably similar transcriptionally and morphologically to age-matched human embryonic hearts.
[Nature Communications] |
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| To uncover the pathomechanism of Autosomal Recessive Renal Tubular Dysgenesis (AR-RTD), differentiation of ACE-/- and AGTR1-/- iPSCs and AR-RTD patient-derived iPSCs into kidney organoids were leveraged.
[Nature Communications] |
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| Scientists demonstrated that embryoid bodies and various organoid models could be optimized by using the small molecule cocktail of chroman 1, emricasan, polyamines, trans-ISRIB (CEPT), a polypharmacological approach that ensured cytoprotection and cell survival.
[Biofabrication] |
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| Researchers reported the establishment of 16 endometrial cancer (EC) PDXOs with or without FGFR2c expression. In vitro treatment of five EC PDXOs with BGJ398 showed significant cell death in three models with FGFR2c expression.
[npj Precision Oncology] |
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| The authors conducted scRNA-seq for paired primary tumors and organoids from one cholangiocarcinoma and two pancreatic ductal adenocarcinoma patients.
[Cancer Letters] |
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| Investigators utilized brain organoids with optic vesicles to systematically analyze the neurotoxicity of As and Pb.
[Environmental Research] |
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| Scientists investigated the involvement of cystatin B in synaptic plasticity, using synaptosomes from human cerebral organoids as well as from rodents’ brain.
[Molecular Neurobiology] |
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| Researchers described the stepwise and fully 3D production of hepatic organoids from hPSCs. They optimized every differentiation step by screening for optimal concentrations and timing of differentiation signals in each differentiation step.
[Differentiation] |
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| Investigators discuss the expanding range of organ building blocks (OBB), presents the rapidly evolving collection of bioprinting and bioassembly methods using these OBB, and outlines the advantages, challenges, and future perspectives of employing OBB in organ printing.
[Tissue Engineering Part A] |
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| To better understand the origin and application value of organoids, the authors review the developmental history and advancement of inner ear organoid research.
[Fundamental Research] |
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| The University of Toronto’s Medicine by Design initiative and CCRM, a non-profit that supports the development and commercialization of regenerative medicines, are launching a new strategic alliance that aims to unlock Toronto’s potential as a world-leading ecosystem for regenerative medicine.
[The University of Toronto] |
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| Some researchers publish a new paper every five days, on average. Data trackers suspect not all their manuscripts were produced through honest labor.
[Nature] |
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| February 27 – 28, 2024
London, England, United Kingdom |
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| | H. Lee Moffitt Cancer Center & Research Institute – Tampa, Florida, United States |
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| | UCLA Blood Stem Cell Research Center – Los Angeles, California, United States |
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| | Cedars-Sinai – Los Angeles, California, United States |
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| | Ottawa Hospital Research Institute – Ottawa, Ontario, Canada |
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| | Swammerdam Institute for Life Sciences – Amsterdam, Netherlands |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
