 | | Vol. 5.05 – 8 February, 2024 |
| |
|
|
| Scientists used orthogonal induced differentiation of human pluripotent stem cells carrying a regulatable ETV2 allele, to rapidly and efficiently induce endothelial differentiation.
[Advanced Materials] |
|  |
|
|
| PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| Investigators described the generation of trophoblast organoids using human trophoblast stem (TS) cells. Following treatment with three kinds of culture medium, TS cells formed spherical organoids with a single outer layer of syncytiotrophoblast cells that displayed a barrier function.
[Nature Communications] |
|
|
|
| A tumor-metastasis-mimicked Transwell-integrated organoids-on-a-chip platform for precisely evaluating tumor metastatic potential was developed.
[Small] |
|
|
|
| Researchers employed organoids derived from rectal cancer and single-cell whole-genome sequencing to investigate the long-term evolution of subclones in response to radiation.
[Cell Reports] |
|
|
|
| Scientists demonstrated that wild-type LRP10 was secreted via extracellular vesicles and could be internalized via clathrin-dependent endocytosis.
[Cellular and Molecular Life Sciences] |
|
|
|
| Investigators identified genetic association between collagen XI alpha 1 (COL11A1) locus and developmental dysplasia of hip (DDH) with genome-wide association study.
[Clinical and Translational Medicine] |
|
|
|
| Using an advanced human heart organoid system, researchers simulated embryonic heart development under pregestational diabetes–like conditions. These organoids developed pathophysiological features observed in mouse and human studies before.
[Stem Cell Reports] |
|
|
|
| The authors used single-cell sequencing to study the cellular heterogeneity of late-stage mouse inner ear organoid sensory epithelia, which they validated by comparison with data sets of the mouse cochlea and vestibular epithelia.
[iScience] |
|
|
|
| Scientists showed that GFAP-positive astrocytes in cerebral organoids were functional and underwent a range of calcium signaling modalities.
[Biophysical Journal] |
|  |
|
|
|
| Combined with advanced imaging technologies and the power of artificial intelligence, organoids provide new insights that bridge experimental models and real-world clinical scenarios. The authors explore research that embodies this technological synergy.
[Advanced Drug Delivery Reviews] |
|
|
|
|
| China and the United States will once again probably delay the renewal of a decades-old pact to cooperate on science and technology. The two nations have been negotiating for the past six months, but need more time to settle new terms and conditions requested by both sides, sources tell Nature.
[Nature News] |
|
|
|
|
| April 7 – 10, 2024
San Diego, California, United States |
|
|
|
|
|
| | The Genomics Research Center, Academia Sinica – Taipei City, Taiwan |
|
|
|
| | National Institutes of Health – Bethesda, Maryland, United States |
|
|
|
| | Cincinnati Children’s Hospital – Cincinnati, Ohio, United States |
|
|
|
| | Human Technopole – Milan, Italy |
|
|
|
| | Columbia University Irving Medical Center – New York, New York, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
