 | | Vol. 12.15 – 20 April, 2021 |
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| Scientists showed that the enzyme responsible for procollagen C-proteinase activity, bone morphogenetic protein1, selectively suppressed tumor growth and metastasis in cells expressing high levels of COL1A1.
[Nature Communications] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers investigated whether pancreastatin induced islet amyloid peptide aggregation in the pancreas, liver, and skeletal muscles.
[International Journal of Biological Macromolecules] |
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| Scientists identified specific integrin subunits, integrin αv and integrin β5, that were expressed in beta cells. This finding was further elaborated using immunofluorescence analysis of histological sections derived from donor human pancreas.
[Scientific Reports] |
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| Researchers identified ILDR2-interacting proteins to further elucidate the molecular mechanisms underpinning ILDR2 function in pancreatic β-cells.
[Scientific Reports] |
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| The authors explored the molecular mechanism driving impairment of insulin secretion in β cells by the Neuromedin U (NMU)–NMU receptor 1 axis.
[PLoS One] |
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| The research was implemented to figure out the concrete role of pancreatic cancer (PC) cells-derived exosomal long non-coding RNA colon cancer-associated transcript-1 (CCAT1) in PC with its regulation on microRNA-138-5p/high mobility group A1 (miR-138-5p/HMGA1) axis.
[Life Sciences] |
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| Stomatin‑like protein 2 is associated with poor prognosis in several types of cancer, including pancreatic cancer (PC); however, the molecular mechanism of its involvement remains elusive. The study aimed to elucidate the role of this protein in the development of PC.
[Oncology Reports] |
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| Researchers investigated whether miR‐26b regulated CDK14 expression to affect the phenotype of pancreatic cancer cells.
[Journal of Gene Medicine] |
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| Scientists investigated whether kaempferol effectively suppressed pancreatic cancer through upregulation of reactive oxygen species, and explored the underlying molecular mechanism.
[BMC Cancer] |
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| The authors discuss the association between PPARG genetic variants and drug efficacy, as well as the role of alternative splicing and post-translational modifications as contributors to the complexity of PPARγ signaling and to the effects of synthetic PPARγ ligands.
[Current Diabetes Reports] |
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| ERYTECH Pharma announced the completion of enrollment of the first treatment cohort and the escalation to the next and potentially final dose level in a Phase I investigator sponsored clinical trial, named rESPECT, of its lead product candidate eryaspase for the first-line treatment of pancreatic cancer.
[Erytech, Inc.] |
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| Genprex, Inc. announced that the Company has been selected to receive the inaugural “License of the Year” award from the University of Pittsburgh Innovation Institute in recognition of the advances made with its license from University of Pittsburgh toward progressing the development of its gene therapy for diabetes.
[Genprex, Inc.] |
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| October 26 – October 28
Virtual |
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| | Baylor Scott and White Research Institute – Dallas, Texas, United States |
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| | Johns Hopkins All Children’s Hospital – St. Petersburg, Florida, United States |
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| | Columbia University Medical Center – New York, New York, United States |
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| | Rutgers University – New Brunswick, New Jersey, United States |
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| | Karolinska Institutet – Huddinge, Sweden |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
