 | | Vol. 13.28 – 19 July, 2022 |
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| Using knockout human pluripotent stem cells lines of the major m6A demethylase ALKBH5, the authors demonstrated that ALKBH5 played significant regulatory roles in pancreatic organogenesis.
[Nature Communications] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Transplantation of stem cell-derived β cells with ZnT8 loss of function into mice with preexisting diabetes significantly improved glycemia restoration and glucose tolerance.
[Nature Communications] |
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| Scientists employed bromocriptine as a tool to elucidate roles of catecholamine signaling in regulating pancreatic hormone secretion.
[iScience] |
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| Knockdown and exogenous treatment of Galectin-3 binding protein showed that it was required for PDAC cell proliferation, migration, and invasion.
[Proceedings of the National Academy of Sciences of the United States of America] |
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| Researchers used endoscopic ultrasound-guided fine-needle aspiration to collect pancreatic cancer tissues from patients with advanced pancreatic cancer to create organoids, and evaluated their utility in pancreatic cancer research.
[Gut and Liver] |
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| The authors reported that KIF24 depletion suppressed multipolar spindle formation by clustering centrosomes in PDAC harboring supernumerary centrosomes.
[Life Science Alliance] |
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| Pancreatic cancer cells were treated with different concentrations of Periplocin, and real-time cell analysis, colony formation assay, and Ki67 immunofluorescence detection were used to determine cell proliferation.
[Journal of Oncology] |
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| Scientists investigated the role of conditioned medium derived from pancreatic cancer cells and pancreatic stellate cells co-culture on the viability of lymphocytes.
[Scientific Reports] |
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| Investigators discuss how precision medicine in PDAC is moving the needle on survival and explore future opportunities.
[Journal of Clinical Oncology] |
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| The authors provide an overview of the current approaches and achievements in obtaining stem cell-derived β-cells and the numerous challenges, which still need to be overcome to achieve this goal.
[Stem Cell Research & Therapy] |
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| Scientists provide insights into long noncoding RNAs (lncRNAs) as promising biomarkers for tumor metastasis and potential therapeutic strategies for pancreatic cancer.
[Discover Oncology] |
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| Israel and the UAE have signed an agreement to promote cancer and diabetes research, in addition to a joint study on mass vitamin D deficiency in the region.
[Middle East Monitor] |
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| September 12 – 14, 2022
Liverpool, England, United Kingdom |
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| | Carver College of Medicine – Iowa City, Iowa, United States |
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| | Albert Einstein College of Medicine – Bronx, New York, United States |
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| | The Chinese University of Hong Kong – Hong Kong, China |
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| | The University of Tennessee Health Science Center – Memphis, Tennessee, United States |
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| | University Health Network – Toronto, Ontario, Canada |
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