 | | Vol. 13.43 – 1 November, 2022 |
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| The authors addressed the question of whether the rewiring of cancer-associated fibroblasts was affected by different mutations by dissecting the stromal landscape of BRCA-mutated and BRCA Wild-type PDAC.
[Nature Communications] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| To study the role of TYK2 in β-cell development and response to IFNα, scientists generated TYK2 knockout human induced pluripotent stem cells and directed them into the pancreatic endocrine lineage.
[Nature Communications] |
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| In vitro assays using the Beta-TC-6 murine β-cell line suggested that desmoglein-2 supported the actin cytoskeleton as well as the release of cytokines and chemokines.
[Cell Death & Disease] |
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| Researchers described a versatile system to study the impact of tissue architecture on cell phenotype using PDAC as a model system.
[Advanced Healthcare Materials] |
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| Kinesin family 15 (KIF15) was upregulated in metastatic pancreatic cancer tissues, and promoted pancreatic cancer cell migration and invasion.
[Cell Death & Disease] |
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| Scientists developed an in vitro tumor micro environment mimic system comprising pancreatic cancer cells, fibroblasts, and immune cells, and a stress condition, including hypoxia and gemcitabine.
[NPJ Genomic Medicine] |
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| The authors provide an extensive discussion of the mechanisms of diabetes, the roles of endocannabinoid system, as well as current knowledge and future perspectives on the use of medical cannabis and its components in diabetes.
[Trends in Endocrinology and Metabolism] |
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| Investigators provide comprehensive coverage of the adverse events of sodium–glucose cotransporter 2 inhibitors, as well as their management and counseling aspects for Asian type 2 diabetes mellitus populations.
[Journal of Diabetes investigation] |
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| A team of researchers from Monash University has received $750,000 in funding to advance research into the development of a new drug to improve glucose control in people living with type 1 diabetes.
[Monash University] |
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| December 5 – 7, 2022
Virtual |
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| | Helmholtz Munich – Neuherberg, Germany |
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| | AstraZeneca – Gothenburg, Sweden |
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| | Helmholtz Munich – Neuherberg, Germany |
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| | Novo Nordisk – Seattle, Washington, United States |
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| | University of Oxford – Oxford, United Kingdom |
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