 | | Vol. 15.09 – 12 March, 2024 |
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| Researchers conducted a post hoc secondary analysis of a single-center, double-blind, placebo-controlled, parallel-group randomized clinical trial of ergocalciferol vs placebo in youths with newly diagnosed T1D.
[Jama Network Open] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| The authors presented a thermoplastic-based microphysiological system aiming to model the complex microphysiological structure and function of the endocrine pancreas with concurrent real-time read-out capabilities.
[Lab On A Chip] |
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| | To define the cancer cell response to gemcitabine, researchers performed genome-scale CRISPR–Cas9 chemical–genetic screens in PDAC cells and found selective loss of cell fitness upon disruption of the cytidine deaminases APOBEC3C and APOBEC3D.
[Nature Cancer] |
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| Scientists revealed that exosomal lncXIST derived from pancreatic cancer cells was delivered to neural cells and promoted their release of glial-cell-line-derived neurotrophic factor.
[Oncogene] |
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| Investigators screened and identified tiRNA-Val-CAC-2 as highly expressed in pancreatic cancer metastasis samples by transfer RNA-derived small RNA sequencing.
[Oncogene] |
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The authors observed that inhibiting NUAK2 impeded the proliferation, migration, and invasion of pancreatic cancer cells while triggering apoptosis.
[iScience] |
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| The results from studies on the role of autophagy in β-cells and their implication in the development of diabetes as well as the role and mechanisms of non-selective (macro)autophagy, selective autophagy, and other minor forms of autophagy that might occur in β-cells are discussed.
[Journal of Diabetes Investigation] |
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| The US FDA cleared for marketing of the first over-the-counter continuous glucose monitor (CGM). The Dexcom Stelo Glucose Biosensor System is an integrated CGM intended for anyone 18 years and older who does not use insulin.
[FDA] |
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| April 4 – 5, 2024
Cincinnati, Ohio, United States |
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| | City of Hope – Duarte, California, United States |
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| | King’s College London – London, England, United Kingdom |
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| | King’s College London – London, England, United Kingdom |
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| | University of Exeter – Exeter, England, United Kingdom |
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| | Virginia Commonwealth University – Richmond, Virginia, United States |
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