 | | Vol. 11.22 – 19 June, 2020 |
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| In vitro validations confirmed that androgen receptor and ETS-related gene (ERG) regulated a subset of TPCATs, most notably for EPCART.
[Oncogene] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| The authors revealed that dehydrozingerone decreased cell proliferation of rat castration-resistant prostate cancer, PLS10 cells, via induction of the cell cycle arrest in the G1 phase in vitro.
[Molecules] |
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| Palmitic acid decreased the secretion of exosomes in human prostate cancer cells in vitro in a concentration-dependent manner.
[Molecules] |
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| To examine the impact of androgens on the antitumor effect of cabazitaxel (CBZ), investigators used human prostate cancer cell lines with different sensitivity to androgens and CBZ.
[Prostate] |
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| Resveratrol inhibited the migration and invasion of prostate cancer cells, promoted the demethylation of tissue inhibitor of metalloproteinases (TIMP)2 and TIMP3 to upregulate their expressions, and suppressed the expressions of MMP2 and MMP9.
[Prostate] |
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| Scientists showed that their homemade engrailed-2 (EN2) monoclonal antibody could specifically bind endogenous and exogenous EN2 protein in three different prostate cancer cell lines.
[BMC Cancer] |
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| Researchers investigated the target genes of miR-1908 by siRNA screening and identified that spermidine synthase was the key regulator of extracellular vesicle secretion in 22Rv1 cells.
[Cancer Science] |
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| Researchers discovered a promising selectivity of both alkaloids for human prostate cancer cells, including highly drug-resistant lines, compared to non-malignant cells.
[Scientific Reports] |
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| Scientists knocked down KLF5 in prostate cancer cells and found that KLF5 knockdown promoted invasive ability of prostate cancer cells in vitro and in vivo .
[Cell Death & Disease] |
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| The authors summarize clinical trials leading to recent drug approvals and discuss optimal treatment selection.
[Trends in Cancer] |
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| Scientists provide updates on recent advances in elucidating prostate carcinogenesis and explore novel therapeutic and prevention strategies harnessing these discoveries.
[Nature Reviews Cancer] |
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| Bio-Techne Corporation announced that Exosome Diagnostics has established a new partnership with ZERO – The End of Prostate Cancer.
[Bio-Techne Corporation] |
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| A bipartisan group of US senators proposed sweeping—and controversial—changes in how the federal government manages academic research in the face of threats from other countries.
[ScienceInsider] |
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| 2020-10-12 – 2020-10-14
Paris, France | |
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| | Berlin School of Integrative Oncology Charit̩ РBerlin, Germany |
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| | Universitätsklinikum Tübingen – Tübingen, Germany |
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| | Karolinska Institutet – Solna, Sweden |
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| | The Vita-Salute San Raffaele University – Milan, Italy |
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| | Augusta University – Augusta, Georgia, United States |
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| | Uniformed Services University of the Health Sciences – Bethesda, Maryland, United States |
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| | Karolinska Institutet – Solna, Sweden |
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| | Oklahoma Medical Research Foundation – Oklahoma City, Oklahoma, United States |
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