| Vol. 11.25 – 10 July, 2020 |
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| Using prostate adenocarcinoma and therapy-induced neuroendocrine prostate cancer cell models, researchers demonstrated that LIN28B induced a stem-like gene network, neuroendocrine biomarkers, and neuroendocrine cell morphology. [Journal of Clinical Investigation] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| By a lineage tracing approach, scientists showed that the two luminal cell populations were independently sustained. [Stem Cells] |
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| Researchers investigated two methods for in vitro cultivation of putative prostate cancer stem cells based on ‘high-salt agar’ and ‘monoclonal cultivation’. [Scientific Reports] |
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| Scientists demonstrated that LINC00920 transcription was directly activated by ERG, an oncogenic transcription factor overexpressed in 50% of prostate cancers. [Molecular Cancer Research] |
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| The CCK-8 experiment demonstrated that carnitine palmitoyltransferase 1B (CPT1B) overexpression in C4-2 cells did not significantly increase the ability of enzalutamide resistance. However, overexpression of CPT1B in C4-2R cells significantly increased the enzalutamide resistance. [Prostate] |
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| In vivo and in vitro experiments exhibited that miR‐196a promoted prostate cancer proliferation and expedited G1/S‐phase progression through the downregulation of p27kip1 protein. [Prostate] |
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| Researchers assessed the effect of cancer-derived immunoglobulin G on the migratory, invasive and proliferative abilities of prostate cancer cells in vitro and in vivo. [Prostate] |
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| The anticancer potential of the fractions was evaluated in vitro using different cancer cell lines: human colorectal carcinoma and PC-3. Fibroblast-like cells of L929 obtained from subcutaneous adipose tissue of mouse were used as normal cells. [Molecules] |
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| Scientists reported that the expression of TXNIP was significantly decreased in prostate cancer and associated with clinicopathological features. Overexpression of TXNIP could significantly inhibit PC‐3 cells proliferation, migration, invasion and glucose uptake. [Cell Biology International] |
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| The authors provide an overview of tumor vascular characteristics that limit the effect of radiation and establish a rationale for exercise as adjunct therapy during prostate cancer radiotherapy. [Prostate Cancer and Prostatic Diseases] |
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| Studies of the biological interactions and molecular links may explain the reasons for the greater severity of SARS-CoV-2 in men, and specifically in the age group at risk for prostate cancer [Communications Biology] |
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| RefleXion Medical and Telix Pharmaceuticals Limited announced a strategic collaboration to investigate the clinical utility of combining the companies’ technologies to improve treatment for high-risk or recurrent prostate and aggressive kidney cancers. [RefleXion Medical] |
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| International students completing their medical and doctoral degrees in the US are wrestling with frustration and uncertainty following the release of federal rules this week that could bar them from staying in the country. [STAT News] |
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| A new US immigration policy, which threatens to revoke visas for certain international students if they are not taking in-person classes, is stirring panic and confusion and causing some universities to push back with lawsuits. [Science] |
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| August 17 – August 19 Virtual |
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| University of Maryland – Baltimore, Maryland, United States |
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| The Vita-Salute San Raffaele University – Milan, Italy |
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| Berlin School of Integrative Oncology Charité – Berlin, Germany |
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| University of Freiburg – Freiburg, Germany |
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| West Virginia University – Morgantown, West Virginia, United States |
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