| Vol. 12.30 – 13 August, 2021 |
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| Scientists showed, using prostate as a model tissue, that primary organoids and freshly isolated epithelial cells could be CRISPR edited ex vivo using Cas9-sgRNA ribotnucleoprotein complex technology. [Proceedings of the National Academy of Sciences of the United States of America] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| The authors found that lysine acetyltransferase 2 A (KAT2A) expression was increased in abiraterone-resistant prostate cancer C4-2 cells [Cell Death & Disease] |
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| Researchers successfully developed active targeted upconversion nanoparticles as potential probes for dual near-infrared–near-infrared fluorescence and radioactive-guided surgery of prostate-specific membrane antigen prostate cancers. [Journal of Materials Chemistry B] |
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| Colony formation assay showed that the cells with AR, mTOR and DDIT3 knockdown could remarkably mitigate the cell proliferation ability in both PC-3 and LNCap cells. [Ecotoxicology and Environmental Safety] |
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| Scientists investigated the anticancer potential of abundant monophenols from cinnamon, namely, cinnamaldehyde, cinnamic acid, and eugenol, by hypothesizing that they possessed proteasome inhibitory activities capable of suppressing cancer cell proliferation and inducing apoptosis. [Phytotherapy Research] |
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| The authors verified the resistance levels of parental and resistant PC3 prostate cancer cells to bortezomib using WST-1 test. [Medical Oncology] |
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| Scientists analyzed effects of radiation and cetuximab in DU145 and A431 using proliferation, colony-forming-unit- and annexin-V-apoptosis-assays. [Radiation Oncology] |
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| Investigators determined the effect of conjugated cisplatin and low-level laser (LLLT) treatment on the viability of LNCaP prostate cancer cell lines and showed that combination of cisplatin and LLLT could effectively decrease cisplatin-induced cytotoxicity as well as LNCaP cell viability. [Lasers in Medical Science] |
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| Researchers described the striking >90% inhibitory effect of hemin, a natural inducer of the cytoprotective enzyme heme oxygenase-1, on Mycoplasma hyorhinis replication in chronically infected LNCaP prostate cancer cells. [FEBS Openbio] |
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| The authors discuss perturbation of cell death in prostate cancer and how new therapeutics could improve treatment outcome in prostate cancer. [Cancer Letters] |
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| Scientists describe recent advancements in isolation and detection technology and the strength and weaknesses of the three circulating biomarkers. [Lab on a Chip] |
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| Noxopharm Limited has reported pre-clinical data confirming a survival benefit of adding Veyonda® to 177lutetium-PSMA-617 (LuPSMA) treatment in prostate cancer. [Noxopharm Limited (BusinessWire, Inc.)] |
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| October 14, 2021 Wädenswil, Switzerland |
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| Cornell University – New York City, New York, United States |
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| The University of British Columbia – Vancouver, British Columbia, Canada |
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| Dalhousie University – Halifax, Nova Scotia, Canada |
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| University of Kentucky – Lexington, Kentucky, United States |
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| Augusta University – Augusta, Georgia, United States |
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