 | | Vol. 12.32 – 27 August, 2021 |
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| The authors reported that plasma-derived circulating vesicles consisting of CD9 and double-positive for CD9 and Prostate Specific Membrane Antigen were increased in patients with advanced metastatic prostate cancer.
[Journal of Extracellular Vesicles] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| In tumor cell lines, the uptake of the radioligands was increased when using low molar concentrations of the respective ligand. The observed saturation effect at high ligand concentrations was more pronounced for LNCaP cells that express PSMA at lower levels than for PC-3 PIP cells.
[European Journal of Nuclear Medicine and Molecular Imaging] |
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| In prostate cancer cell lines, transgenic mouse models and human prostate tumor cohorts, scientists confirmed that YAP1 RNA and YAP1 protein expression were silenced in neuroendocrine prostate cancer.
[Journal of Pathology] |
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| Researchers demonstrated that selective deletion of stromal androgen-receptor expression in prepubescent Shh responsive Gli1-expressing cells significantly impeded pubertal prostate epithelial growth and development.
[Development] |
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| To identify long-term changes in gene expression after irradiation, PC3 and LNCaP prostate cancer cells were irradiated with either a single dose or a fractionated regimen of 10 fractions.
[Cancer Immunology] |
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| Scientists reported the molecular interactions of indoline derivative, HIC, with P2Y1R. In vitro analysis has shown increased apoptosis of PCa-cells, PC3, and DU145, upon specific interaction of P2Y1R-HIC.
[International Journal of Biological Macromolecules] |
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| In primary and metastatic prostate cancer tissues, circSMARCA5 was significantly downregulated compared with normal controls. Functionally, circSMARCA5 exhibited a suppressive effect on prostate cancer cells’ metastasis and growth.
[Aging] |
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| Investigators combined FX-9 with the currently approved therapeutic agents doxorubicin, carboplatin, the demethylating substance azacitidine as well as further potentially antitumorigenic agents such as dichloroacetic acid in order to evaluate the respective synergistic potential.
[PLOS One] |
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| Scientists provided the expression and the predictive significance of miR-1273 g-3p in prostate cancer. The effects on cell biological activities were also investigated.
[Molecular Biotechnology] |
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| The development of immunotherapy in cancer treatment has brought an exciting era of antiprostate cancer therapy through antitumor immune responses.
[Prostate] |
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| Samyang Biopharm USA, Inc. global biotech subsidiary of the Samyang Holdings Pharmaceuticals Corp. announced today that the company has entered into a three-year research collaboration with Dr. Hyun-Sung Lee, Assistant Professor of Surgery and Director of the Systems Onco-Immunology Laboratory at Baylor College of Medicine.
[Samyang Biopharm USA, Inc. (BusinessWire, Inc.)] |
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| September 28 – 29, 2021
Virtual |
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| | Duke University – Durham, North Carolina, United States |
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| Baylor College of Medicine – Houston, Texas, United States |
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| | Dana-Farber Cancer Institute- Boston, Massachusetts, United States |
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| | Cornell University – New York City, New York, United States |
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| The University of British Columbia – Vancouver, British Columbia, Canada |
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