 | | Vol. 13.09 – 11 March, 2022 |
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| Researchers investigated the combination of IL-15 with an intratumoral anti-CD40 monoclonal antibody (mAb) in a dual tumor TRAMP-C2 murine prostate cancer model and expanded the regimen to include an anti-PD-1 mAb.
[Clinical Cancer Research] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| By combining organoids technology with click-chemistry coupled mass spectrometry, investigators demonstrated a prominent role of ERG in remodeling the protein secretome of prostate progenitors.
[Cancer Letters] |
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| Scientists demonstrated a linear calibration curve from cell lysate and correlate lysate protein with mRNA from cultured prostate cancer cells.
[ACS Sensors] |
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| Untargeted RNA sequencing, proteomics, and metabolomics were performed on xenografts derived from three independent sets of hormone naïve and matched CRPC human cell line models of local, lymph node and bone metastasis grown as murine orthografts.
[iScience] |
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| The authors suggested that miR-5195-3p functioned as a tumor suppressor by targeting Cyclin L1 (CCNL1) in prostate cancer.
[Cellular & Molecular Biology Letters] |
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| The changes in gene expression profiles of multidrug resistant prostate cancer cells that were established in response to docetaxel were determined using microarray analysis.
[Fundamental & Clinical Pharmacology] |
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| The antiproliferative activity of target compounds in four human cancer cells, PC-3, MCF-7, HepG-2 and MGC-803, was evaluated by thiazole blue.
[Bioorganic & Medicinal Chemistry Letters] |
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| Scientists investigated the effect of Microcystin-LR on prostate cancer cell invasion and its underlying mechanisms.
[Toxicon] |
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| Related substances of synthesized polyphenolic compounds 4 and 5 effects on prostate cell viability were evaluated by MTT analysis, and their effects on migration were examined by in vitro scratch analysis.
[Chemistry & Biodiversity] |
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| The authors conduct a systematic review and meta-analysis to determine the incidence of late genitourinary toxicity relying on radiation therapy oncology group and common terminology criteria for adverse events grade as well as the incidence of specific genitourinary toxicity.
[Prostate Cancer and Prostatic Diseases] |
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| Orion’s collaboration partner Bayer announced the submission to the Ministry of Health, Labor and Welfare in Japan for an additional indication for the oral androgen receptor inhibitor darolutamide for the treatment of patients with prostate cancer with distant metastasis.
[Orion Corporation] |
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| | Dana-Farber Cancer Institute – Boston, Massachusetts, United States |
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| | The University of British Columbia – Vancouver, British Columbia, Canada |
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| | Singapore-MIT Alliance for Research and Technology (SMART) Centre – Singapore, Singapore |
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| | University of Nebraska Medical Center – Omaha, Nebraska, United States |
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| | University of Washington – Seattle, Washington, United States |
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Cancer Stem Cell News
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