 | | Vol. 13.26 – 4 November, 2022 |
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| Using single-cell multiomics analyses, researchers investigated the dynamics of cellular heterogeneity, transcriptome regulation, and microenvironmental factors in 107,201 cells from genetically engineered mouse prostate cancer samples with complete time series of tumor evolution seen in patients.
[Cancer Cell] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators performed analytical validation of a circulating tumor cell multiplex RNA qPCR assay to identify the limit of quantification in cell lines, synthetic cDNA, and patient samples.
[Journal of Clinical Investigation] |
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| Using the highly sensitive enrichment-based sequencing technology, the authors provided analysis of 60 and 175 plasma DNA methylomes from patients with localized and metastatic prostate cancer, respectively.
[Nature Communications] |
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| Scientists demonstrated that loss of androgen receptor in stromal sonic-hedgehog Gli1-lineage cells diminished prostate epithelial oncogenesis and tumor development using in vivo assays and mouse models.
[Nature Communications] |
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| To evaluate the performance of nanocarriers in improving imaging contrast and therapeutic efficacy, researchers designed and synthesized prostate cancer-targeting starPEG nanocarriers with one or three prostate-specific membrane antigen-targeting urea-based ACUPA ligands.
[ACS Applied Materials & Interfaces] |
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| Investigators interrogated B7-H3 expression and its regulation in metastatic castration-resistant prostate cancer since B7-H3 could be an excellent therapy target due to its overexpression in prostate cancer with minimal expression in normal tissues and association with poor prognosis.
[npj Precision Oncology] |
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| Scientists focused on urinary proteomes of patients with prostate cancer and identified tumor-modifying proteins in the samples before and after prostatectomy.
[Therapeutic Advances in Medical Oncology] |
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| Researchers investigated microRNAs in exosomes isolated from blood and post-prostatic-massage urine of chronic prostatitis/chronic pelvic pain syndrome type IIIb patients and healthy men.
[Molecular Oncology] |
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| Investigators determined heat shock protein B8 (HSPB8) expression in prostate cancer (PC) tissues by immunohistochemical staining and explored the in vitro functions of HSPB8 using HSPB8 knockdown DU145 and LNcap PC cell lines.
[Biochemistry and Cell Biology] |
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| The authors review clinical outcomes for MRI-guided external beam radiotherapy focal boost to intraprostatic lesions.
[European Urology Oncology] |
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| Scientists review the current status and the lingering challenges of the rapidly evolving clinical space of oligometastatic prostate cancer.
[Journal of Nuclear Medicine] |
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| Senhwa Biosciences, Inc. announced that their first patient had been successfully dosed, in a Phase I clinical study evaluating the combined treatment with Senhwa’s Pidnarulex and Pfizer’s PARP inhibitor, Talazoparib, in patients with metastatic castration-resistant prostate cancer.
[Senhwa Biosciences, Inc.] |
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| March 6 – 8, 2023
Paris, France |
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| | Novartis – Minneapolis, Minnesota, United States |
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| | University of Illinois Chicago – Chicago, Illinois, United States |
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| | Baylor College of Medicine – Houston, Texas, United States |
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| | Columbia University Irving Medical Center – New York, New York, United States |
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| | Sidney Kimmel Cancer Center – Philadelphia, Pennsylvania, United States |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
