 | | Vol. 13.29 – 2 December, 2022 |
| |
|
|
| Scientists observed an enrichment of transcription factor genes including HNF1B within prostate cancer (PCa) risk-associated regions. They found a strong expression quantitative trait locus for HNF1B and multiple potential causal variants involved in the regulation of HNF1B expression in PCa.
[Nature Communications] |
|  |
|
|
| PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| Researchers showed that AT-rich interactive domain-containing proteins 1 A (ARID1A), a subunit of the SWI/SNF chromatin remodeling complex, functioned downstream of inflammation-induced IKKβ activation to shape the immunosuppressive tumor microenvironment.
[Nature Communications] |
|
|
|
| Saikosaponin A (SSA) was posed as a novel quiescent cancer cell (QCC)-eradicating agent by aggravating autophagy in QCCs. In combination with the current therapy, SSA had potential to improve treatment effectiveness and to prevent cancer recurrence.
[Cancer Letters] |
|
|
|
| The authors reported an approach for suppressing reactivated androgen receptor (AR) signaling in the castration-resistant prostate cancer stage. A combination of tautomycin and enzalutamide synergistically inhibited cell proliferation and AR signaling in LNCaP, C4-2, and 22RV1 cells.
[Cell Death Discovery] |
|
|
|
| The LNCaP-androgen dependent cell line was cultured and passaged 60 times over 16 months. The morphology of the LNCaP-androgen independent (AI) cell line was observed. Androgen receptor levels identification were detected in qRT-PCR and Western blot assay.
[BMC Molecular and Cell Biology] |
|
|
|
| Reproduction had been investigated in the nematode Steinernema siamkayai, using a fermentation system supplemented with different concentrations of exogenous hexapeptides. Peptide structure-activity relationships had also been studied using prostate cancer and other mammalian cells in vitro.
[PLoS One] |
|
|
|
| The anti-prostate cancer of acidic exo-polysaccharide produced from marine Bacillus sp. NRC5 was determined using 7,12-dimethylbenz-(a)-anthracene (DMBA) and DMBA-induced prostate cancer in male Sprague Dawley rats.
[Current Microbiology] |
|
|
|
| The mode of action of progesterone on endoplasmic reticulum-associated degradation, unfolded protein response, and androgen receptor signaling in prostate cancer was investigated by cell culture studies using LNCaP and 22Rv1 cells.
[Molecular Biology Reports] |
|
|
|
| Researchers synthesized an aryl ester compound from quinoline-2-carboxylic acid to evaluate its apoptotic, cell cycle blockade, and antiproliferative activity on the prostate cancer cell lines (PC3).
[Applied Biochemistry and Biotechnology] |
|  |
|
|
|
| Preclinical prostate cancer models include standard, genetically modified and patient-derived cell lines, spheroid and organoid culture models, scaffold and hydrogel cultures, tissue slices, tumor xenograft models, patient-derived xenograft models, as well as transgenic and knockout mouse models.
[Nature Reviews Urology] |
|
|
|
|
| Cipla announced the launch of Leuprolide Acetate Injection Depot 22.5mg. The product was approved by the US FDA based on a New Drug Application submitted under the 505(b)(2) regulatory pathway.
[Cipla] |
|
|
|
| Dr. Pierre-Antoine Dugué was awarded the Victorian Cancer Agency Mid-Career Research Fellowship worth $681,808. The fellowships are part of an $8.5 million plan to fund new ways to detect and treat a host of cancers.
[Monash University] |
|
|
|
|
| April 23 – 28, 2023
Cancun, Mexico |
|
|
|
|
|
| | Indiana University School of Medicine – Bloomington, Indiana, United States |
|
|
|
| | Columbia University in the City of New York – New York, New York, United States |
|
|
|
| | STEMCELL Technologies, Inc. – Boston, Massachusetts, United States |
|
|
|
| | Imperial College London – London, England, United Kingdom |
|
|
|
| | Dana-Farber Cancer Institute – Boston, Massachusetts, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
