 | | Vol. 14.01 – 13 January, 2023 |
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| Investigators demonstrated that RING finger domain protein TRIM28 bound and promoted ubiquitination and degradation of CDK4/6-phosphorylated retinoblastoma protein (RB).
[Cancer Research] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| In a subset of prostate cancer organoid culture and xenograft models, inhibition of Wnt synthesis stimulated growth, while WNT5a or a WNT5a mimetic peptide markedly suppressed tumor growth.
[Cancer Research] |
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| Scientists identified the up-regulation of chaperone-mediated autophagy in response to acute androgen receptor pathway inhibition (ARPI) stress, which persisted in castration-resistant prostate cancer (PCa), previously undefined in PCa.
[Oncogene] |
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| Researchers designed a robust machine learning-based framework to comprehensively explore the impact of DNA replication stress on prognosis and treatment in five prostate cancer bulk transcriptomic cohorts with a total of 905 patients.
[Journal of Translational Medicine] |
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| The authors investigated the role of ribosomal protein L22-like1 in prostate cancer progression and the mechanisms involved.
[Journal of Cellular and Molecular Medicine] |
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| Scientists elucidated how primary prostate cancer (PCa) cells cooperated with distal osteoblasts and contributed to the vicious cycle that led to metastatic PCa.
[International Journal of Biological Sciences] |
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| Investigators reported the fabrication of highly pure magnetosomes that were synthesized by magnetotactic bacteria using pharmaceutically compatible growth media.
[Applied Microbiology and Biotechnology] |
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| Researchers investigated if a magnetic resonance imaging-based model reduced postoperative biochemical failure incidence in patients with prostate cancer.
[Scientific Reports] |
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| The authors tested, for the first time, the combination of an Enhancer of Zeste 2 (EZH2) inhibitor with a BET inhibitor in metastatic prostate cancer cells.
[Journal of Enzyme Inhibition and Medicinal Chemistry] |
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| The sol–gel auto-combustion preparation method using two different fuel agents, citric acid and glycine, was used to synthesize CoFe2O4 nanoparticles.
[Journal of Materials Science: Materials in Electronics] |
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| A yeast reporter system enables a high-throughput study of the interaction between each ligand and androgen receptor (AR) mutant by visual observation of yeast colony formation and can be applied to high-throughput AR compound screening for the treatment of prostate cancer.
[Nature Reviews Urology] |
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| Dr. Manoj Mishra has been awarded a four-year, $2,631,400 grant from the American Cancer Society’s Diversity in Cancer Research Institutional Development to continue Alabama State University’s cutting-edge cancer research program and outreach.
[Alabama State University] |
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| April 14 – 19, 2023
Orlando, Florida, United States |
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| | Pompeu Fabra University – Barcelona, Spain |
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| | Stanford Medicine – Stanford, California, United States |
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| | University Medical Center Freiburg – Freiburg, Germany |
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| | UTHSC-Houston – Houston, Texas, United States |
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| | The University of British Columbia – Vancouver, British Columbia, Canada |
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