 | | Vol. 14.10 – 17 March, 2023 |
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| Scientists thoroughly studied the effects of selected mutations that span the complete dimer interface of the androgen receptor ligand–binding domain using x-ray crystallography in combination with in vitro, in silico, and cell-based assays.
[Science Advances] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers showed that CDKL3 was significantly upregulated in prostate cancer tissues compared with adjacent normal tissues, and was significantly positively correlated with tumor malignancy.
[Cell Death & Disease] |
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| Scientists studied the role of tripartite motif-containing 28 (TRIM28) in prostate cancer progression in vivo and generated a genetically-engineered mouse model, combining prostate-specific inactivation of Trp53, Pten, and Trim28.
[Oncogene] |
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| Investigators determined the contribution of the ARFome to the morphology and migration of prostate cancer cells within 3D culture.
[Journal Of Cell Biology] |
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| Scientists showed focally amplified long non-coding RNA on chromosome 1 (FALEC) was upregulated in post-castration tissues and castration-resistant prostate cancer cells, and increased FALEC expression was associated with poor survival in post-castration prostate cancer patients.
[Cellular Oncology] |
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| Researchers identified a novel lncRNA that was down-regulated in prostate cancer and correlated with tumor progression characteristics.
[Journal Of Cancer Research And Clinical Oncology] |
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| WD repeat domain 3 (WDR3) was negatively correlated with USF2, which was degraded by promoting ubiquitination of USF2, and USF2 interacted with promoter region-binding elements of RASSF1A to depress prostate cancer stemness and growth.
[The Journal Of Gene Medicine] |
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| Scientists reported for the first time a long non-coding RNA-PCMF1 which promoted the progression of epithelial-mesenchymal transition in prostate cancer cells.
[Molecular Biotechnology] |
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| The authors uncovered the relationship between cell density and cancer stem cells (CSCs), and the role of the Warburg effect in regulating CSC-like characteristics.
[Biology Open] |
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| The role of the EMT mechanism in regulating urological cancer progression is evaluated and for this purpose, a description of urological cancers, pathogenesis, and some basic information about their metastasis potential is provided.
[Environmental Research] |
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| Curium confirmed that the company has no foreseeable supply challenges of 177Lu-PSMA-I&T for the company’s ECLIPSE Phase III clinical trial ongoing in the USA, France, Spain, and Italy.
[Curium] |
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| April 24 – 26, 2023
Hinxton, England, United Kingdom |
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| | Newcastle University – Newcastle upon Tyne, England, United Kingdom |
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| | Medical College of Wisconsin – Milwaukee, Wisconsin, United States |
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| | University of Miami – Miami, Florida, United States |
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| | Dana-Farber Cancer Institute – Boston, Massachusetts, United States |
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| | Vancouver Prostate Centre – Vancouver, British Columbia, Canada |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
