| Vol. 14.12 – 31 March, 2023 |
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| Researchers identified functional androgen-insensitivity-syndrome-patient mutations in the formin and actin nucleator DAAM2, where its localization correlated with that of the androgen receptor to form actin-dependent transcriptional droplets in response to dihydrotestosterone. [Nature] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists found that MYC reshapes the chromatin architecture of prostate cancer cells by interacting with CTCF protein. [Nature Communications] |
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| Investigators found that HOXB3 protein level was an independent risk factor of prostate specific antigen progression and death in patients with metastatic castration-resistant prostate cancer. [Cell Death & Disease] |
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| MBTPS2 was implicated in progressive prostate cancer and may mechanistically involve its effects on fatty acid and cholesterol metabolism. [British Journal Of Cancer] |
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| Scientists investigated the impact of neuronal PAS domain-containing protein 2 (NPAS2) on cell growth and glucose metabolism in prostate cancer. [BMC Cancer] |
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| Researchers found pterostilbene, a natural agent with potent anticancer activity, could enhance expression of major histocompatibility complex class I chain-related proteins A and B on prostate cancer cells surface, which are ligands of the natural killer group 2 member D (NKG2D) expressed by natural killer (NK) cells. [Heliyon] |
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| Scientists examined whether pharmacological inhibition of β2-adrenergic receptor (β2-AR) increased cell sensitivity to docetaxel in castration-resistant prostate cancer cells and the possible regulation of β2-AR in cell autophagy and apoptosis and the several molecular mechanisms. [Biochemical And Biophysical Research Communications] |
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| Researchers separated the urogenital mesenchyme from the urogenital epithelium (UGE) and tested candidate growth factors to show that when FGF10 is present, testosterone is not required for initiating prostate budding from the UGE. [Developmental Biology] |
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| Investigators found that miR-629 was markedly up-regulated in prostate cancer which was determined using the cancer genome atlas dataset, clinical tissues, and cell lines. [Hormone And Metabolic Research] |
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| The authors summarize preclinical and clinical evidence suggesting that altered calcium signaling is a crucial component of the molecular re-programming that drives prostate cancer progression. [Nature Reviews Urology] |
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| Propanc Biopharma, Inc. announced that PRP suppressed the TGF-β pathway and the tumor microenvironment in pancreatic cancer, elucidated by Mrs. Belén Toledo Cutillas MSc, at the laboratory of Professor Macarena Perán, PhD, University of Jaén, Granada, Spain. [Propanc Biopharma, Inc.] |
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| April 16 – 19, 2023 Snowbird, Utah, United States |
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| Novartis – East Hanover, New Jersey, United States |
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| Medical College of Wisconsin – Milwaukee, Wisconsin, United States |
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| Newcastle University – Newcastle upon Tyne, England, United Kingdom |
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| Medical College of Wisconsin – Milwaukee, Wisconsin, United States |
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| University of Miami – Miami, Florida, United States |
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