 | | Vol. 14.18 – 19 May, 2023 |
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| Researchers examined zinc finger DHHC (ZDHHC) family gene expression in human tissue panels and identified ZDHHC7 as a prostate cancer-relevant member.
[Oncogene] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists investigated the prognostic value of dichotomized aneuploidy scores as well as circulating tumor cell counts in 131 metastatic CRPC patients prior to treatment with cabazitaxel.
[Molecular Oncology] |
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| A series of novel thiohydantoin based androgen receptor (AR) antagonists with efficient degradation against AR were designed, synthesized, and evaluated
[European Journal of Medicinal Chemistry] |
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| Researchers showed that gonadal androgens suppressed ectopic proliferation in the adrenal cortex and determined the selective regulation of the WNT-related genes Axin2 and Wnt4.
[Disease Models & Mechanisms] |
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| The authors investigated the effect of asiatic acid on prostate cancer metastasis and to better understand its molecular mechanisms of action.
[European Journal of Pharmacology] |
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| Cell-based studies showed that harmine treatment inhibits CRPC cell proliferation with an IC50 of ∼14 μM. The CPRC cells treated with harmine resulted in reactivating silenced hypermethylated genes compared to the untreated cells
[ACS Chemical Biology] |
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| Investigators evaluated the protective effect of molecular iodine and testosterone on hyperestrogenism-induced prostate inflammation.
[Molecular and Cellular Endocrinology] |
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| Scientists identified Paraspeckle Component 1 (PSPC1) as an interacting protein of Lysine Demethylase 5C (KDM5C), suggesting that these proteins might function together in prostate cancer.
[Human Pathology] |
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| To determine the clinical significance and function of Gleason-Score-related genes in prostate adenocarcinoma, prostate cancer cell lines were cultured and transfected with Gleason-Score-related genes to explore the function of MT1L in vitro.
[International Journal of Biological Markers] |
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| Investigators discuss how prostate organoid technology is currently being used, the promising areas of future therapeutic applications, and the current obstacles to be overcome.
[Journal Of Clinical Investigation] |
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| The election result comes as the country was pursuing plans to move from a heavy-industry-based economy to one geared towards innovation, known as Thailand 4.0 — but what the new government will mean for those plans remains unclear.
[Nature] |
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| June 3 – 7, 2023
San Diego, California, United States |
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| | The Georgia Cancer Center – Augusta, Georgia, United States |
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| | The Brady Urological Institute – Baltimore, Maryland, United States |
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| | Harvard T.H. Chan School of Public Health – Boston, Massachusetts, United States |
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| | University of Miami Desai Sethi Urology Institute – Miami, Florida, United States |
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| | Case Western Reserve University – Cleveland, Ohio, United States |
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