 | | Vol. 14.22 – 16 June, 2023 |
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| Through high-resolution genome-wide single-cell DNA methylation sequencing, scientists identified 40 core domains that were uniformly hypomethylated from the earliest detectable stages of prostate malignancy through metastatic circulating tumor cells (CTCs).
[Cell] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| An enhanced intracellular magnetic fluid hyperthermia was applied in vitro to treat prostate cancer cells with minimum invasiveness, toxicity, and highly specific targeting.
[ACS Applied Materials & Interfaces] |
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| Investigators examined the expression, regulation and therapeutic potential of RIOK1 in prostate cancer (PCa). RIOK1 mRNA and protein expression were elevated in PCa tissue samples and correlated with proliferative and protein homeostasis related pathways.
[The American Journal of Pathology] |
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| The authors explored the biological function of E3 ubiquitin ligase F-box only protein 22 (FBXO22) in prostate cancer metastasis and its specific regulation mechanism.
[The American Journal of Pathology] |
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| Researchers demonstrated that six transmembrane epithelial antigen of the prostate 1 (STEAP1) overexpression was associated with prostate cancer progression and aggressiveness.
[Biochimica Et Biophysica Acta-Molecular Cell Research] |
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| Using viability assays, investigators confirmed that androgen receptor variant 7-positive prostate cancer cells were less sensitive to treatment with cabazitaxel and an anti-androgen-enzalutamide.
[Translational Oncology] |
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| In vitro experiments showed the ability of myeloperoxidase to potentiate the reactive oxygen species (ROS) production and inflammation on prostate epithelial cells.
[Inflammation] |
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| Scientists evaluated the in vitro anticancer mechanisms of C. sativus seed oil and its possible chemopreventive potential on benzo(a)pyrene-induced prostate cancer in Wistar rat.
[Environmental Toxicology] |
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| The authors investigated the effects of two different dose fractionations of radiation on the activation of the Type-I interferon (IFN)-pathway in three hormone-dependent and independent prostate cancer cell lines.
[Cytokine] |
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| Investigators review the current understanding of the role of microRNAs and exosomes in the pathogenesis and their significance in prostate cancer prognosis, early diagnosis, chemoresistance, and treatment.
[Pathology – Research and Practice] |
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| Benjamin Martin, PhD, Associate Professor at Stony Brook University has received a $2 million grant from the National Institutes of Health’s National Institute of General Medical Sciences to conduct research to understand the molecular and cell biology of neuromesodermal progenitors.
[Stony Brook University] |
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| September 4 – 7, 2023
Surrey, England, United Kingdom |
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| | Cedars Sinai Medical Center – Los Angeles, California, United States |
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| | University of Texas MD Anderson Cancer Center – Houston, Texas, United States |
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| | Georgia Cancer Center at Augusta University – Augusta, Georgia, United States |
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| | City of Hope – Duarte, California, United States |
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| | The Brady Urological Institute – Baltimore, Maryland, United States |
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