 | | Vol. 14.26 – 14 July, 2023 |
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| The prodrug tested demonstrated a dose-dependent effect to reduce the tumor volume of 22Rv1 prostate cancer xenografts without observed toxicity.
[Journal Of Medicinal Chemistry] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Biochemical and cell biology approaches, such as RNA pull-down, western blot, immunostaining, and wound healing assays were used for evaluation of the impact of TWIST1/miR-145/ lnc-ZNF30-3 interactions in prostate cancer cells altered in miRNA and lncRNA expression.
[Biology Direct] |
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| Scientists silenced CDC42 expression in prostate stromal cells, and examined contractility, growth-related functions, and responses to the presumed CDC42 inhibitor, ML141.
[Life Sciences] |
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| The authors investigated the risk of prostate cancer in ever users and never users of rosiglitazone in diabetes patients in Taiwan.
[Frontiers in Endocrinology] |
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| PSMC4 knockdown markedly inhibited cell proliferation, cell cycle and migration in vitro and in vivo, and significantly promoted cell apoptosis.
[Journal of Cellular and Molecular Medicine] |
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| Immunoblotting, quantitative PCR, and calcium imaging were used to validate trpv6 gene status and functional consequences, in both trpv6 -/- and TRPV6 overexpression cell lines.
[Frontiers in Genetics] |
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| A series of 3-phenyl-4-(2-substituted phenylhydrazono)-1H-pyrazol-5(4H)-ones were synthesized and investigated for their cytotoxicity against the PC-3 human cancer cell line, compared to Doxorubicin and Sorafenib as reference drugs.
[Rsc Advances] |
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| The authors evaluated the expression stability of internal reference genes in atorvastatin-treated cancer cell lines, treating both statin-sensitive and statin-resistant cancer cell lines with atorvastatin at seven different concentrations.
[Heliyon] |
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| CCK-8, migration assay and invasion and wound-healing assay were performed to detect proliferation, migration and invasion in prostate cancer cells.
[BMC Urology] |
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| Scientists revisit concepts in androgen receptor signaling and current understandings of androgen receptor signaling-dependent resistance mechanisms, as well as the next frontier of androgen receptortargeting in prostate cancer.
[Journal of Clinical Oncology] |
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| The authors summarize recent advancements made in the therapeutic treatment of metastatic prostate cancer.
[Trends in Cancer] |
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| Health Canada has granted a Notice of Compliance with Conditions for Lynparza® in combination with abiraterone and prednisone or prednisolone for the treatment of adult patients with deleterious or suspected deleterious germline and/or somatic BRCA mutated metastatic CRPC in whom chemotherapy is not clinically indicated.
[AstraZeneca (Newswire)] |
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| August 3, 2023
New York, New York, United States |
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| | City of Hope – Duarte, California, United States |
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| | Novartis – East Hanover, New Jersey, United States |
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| | Albert Einstein College of Medicine – New York City, New York, United States |
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| | University of Miami – Miami, Florida, United States |
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| | NCI Center for Cancer Research – Bethesda, Maryland, United States |
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