 | | Vol. 14.33 – 1 September, 2023 |
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| Scientists reported that the leucine carboxy methyltransferase (LCMT1), which methylated the L309 residue of the C subunit, acted as a suppressor of androgen receptor-addicted prostate cancer.
[Nature Communications] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators indicated that glutathione peroxidase 3 was localized both in the stroma and epithelium of prostate, and down-regulated in benign prostatic hyperplasia samples.
[Journal of Translational Medicine] |
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| The authors discovered the effects and potential mechanisms of Bushen Tongluo formula, a kidney-supplementing and collaterals-unblocking formula, against benign prostatic hyperplasia.
[Phytomedicine] |
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| Researchers found that circDDIT4 was downregulated in prostate cancer (PCa) and functioned as a tumor suppressor during PCa progression.
[Molecular Cancer Research] |
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| Investigators identified baseline Fascin-1 (FSCN1) serum levels to be independently associated with poor survival of abiraterone-treated, but not docetaxel-treated metastatic CRPC patients.
[Prostate Cancer and Prostatic Diseases] |
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| Scientists showed that the ex vivo expansion and activation of cytokine-induced killer cells isolated from primary peripheral blood mononuclear cells induced immune-mediated apoptosis in both human prostate cancer cells.
[Journal Of Cellular And Molecular Medicine] |
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| The authors reconstructed the lncRNA-centered regulatory network of metastatic CRPC and identified the lncRNAs that acted as master regulators.
[Cancer Medicine] |
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| Using PC-3 human prostate cancer cells, investigators found that resistin upregulated the expression of suppressor of cytokine signaling 3 (SOCS3) and SOCS5 mRNA, but not SOCS7 mRNA, in a dose- and time-dependent manner.
[Experimental Biology and Medicine] |
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| Researchers assessed the impact of these androgen receptor (AR) alterations on survival outcomes in a real-world patient population of metastatic CRPC experiencing disease progression on an AR pathway inhibitor.
[The Prostate] |
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| Scientists focus on the potential of targeting hypoxia-inducible factor (HIF) in prostate cancer (PC) and summarize the scientific background of HIF activity in PC.
[Expert Opinion on Therapeutic Targets] |
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| The US government has extended for six months a key symbolic agreement to cooperate with China in science and technology.
[Nature] |
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October 18 – 21, 2023
EMBL Heidelberg and Virtual |
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| | The Sidney Kimmel Cancer Center – Philadelphia, Pennsylvania, United States |
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| | Cedars-Sinai – Los Angeles, California, United States |
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| | University of South Australia – Adelaide, Australia |
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| | Cedars-Sinai – Los Angeles, California, United States |
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| Georgia Cancer Center at Augusta University – Augusta, Georgia, United States |
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