| Vol. 14.35 – 15 September, 2023 |
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| Using chromatin editing technology, scientists showed how such elements promote prostate cancer growth by regulating AR transcriptional activity. [Cancer Discovery] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators explored the roles of Yes-associated protein 1 (YAP) in prostate stem cells, prostate development and regeneration. [Cell Death Discovery] |
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| Scientists showed that well-tolerated doses of canagliflozin suppressed proliferation and survival of androgen-sensitive and insensitive human prostate cancer cells and tumors and sensitized them to radiotherapy. [Communications Biology] |
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| Prostate cancer cells with increased levels of miR-379 showed a significant decrease in proliferation, migration, colony formation, and adhesion to bone cells in vitro. [Frontiers in Oncology] |
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| Researchers attempted to improve the tumor killing capability of prostate-specific membrane antigen-chimeric antigen receptor T (CAR-T) cells by targeting T cell immunoglobulin and mucin domain 3 (TIM3) and transforming growth factor beta (TGFβ) receptor II simultaneously. [International Immunopharmacology] |
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| Scientists demonstrated the potential of DHEP in increasing the tumorigenic properties of DU145 cells along with a focus on the underlying mechanisms. [Bioorganic Chemistry] |
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| The authors investigated the antiproliferative and anti-invasive properties of cannabidiol (CBD) in prostate cancer cells in vitro. CBD inhibited cell viability and proliferation, accompanied by reduced expression of key cell cycle proteins. [Journal Of Natural Products] |
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| A panel of biomarkers was assessed to provide insights into the biological relationship between intraductal carcinoma of the prostate, high-grade prostatic intraepithelial neoplasia, and atypical intraductal proliferations and their relevance to current clinicopathological recommendations. [Virchows Archiv] |
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| Researchers investigated the function of hepatic leukemia factor (HLF) in prostate cancer and its relation to tensin 1 (TNS1). DU145 and PC3 cells overexpressing HLF were established. [Mutagenesis] |
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| The authors specifically summarize the approaches so far applied to inhibit estrogen and androgen availability for receptor binding via inhibiting steroid biosynthesis. [Nature Reviews Cancer] |
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| An Italian newspaper has found duplicated images in eight cancer papers co-authored by the country’s minister of health, Orazio Schillaci. Dr. Schillaci published the papers between 2018 and 2022 while working in the faculty of medicine of the University of Rome Tor Vergata. [Science Insider] |
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| October 11 – 14, 2023 Ottawa, Ontario, Canada |
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| University of Melbourne – Melbourne, Australia |
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| The Sidney Kimmel Cancer Center – Philadelphia, Pennsylvania, United States |
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| University of Texas MD Anderson Cancer Center – Houston, Texas, United States |
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| Cedars-Sinai – Los Angeles, California, United States |
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| Cedars-Sinai – Los Angeles, California, United States |
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