| Vol. 14.43 – 10 November, 2023 |
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| Scientists conducted forward genetic synthetic viability screenings in C. elegans brc-2 (Cebrc-2) mutants and found that Ceubxn-2 inactivation rescued the viability of Cebrc-2 mutants. [Journal Of Clinical Investigation] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| CXCL5-derived tumor cell proliferation and immune suppression were consequences of the melanoma differentiation associated gene-9 (MDA-9)/CXCL5 signaling axis, promoting prostate cancer disease progression. [Proceedings Of The National Academy Of Sciences Of The United States Of America] |
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| Starting from patient cells, the authors established prostate cancer tumoroids and demonstrated that they required TGF-β signaling pathway activity to preserve phenotypical and structural similarities with the tissue of origin. [Matrix Biology] |
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| Using patient peripheral blood polymorphonuclear neutrophils, scientists identified that prostate cancer progression dictated polymorphonuclear neutrophils cell surface markers and gene expression, but not cytotoxicity against prostate cancer. [Cancer Letters] |
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| Researchers demonstrated that increased activity of the Src-JNK pathway in tumors inactivated Notch signaling because of JNK pathway–mediated inhibition of the expression of the gene encoding the Notch S2 cleavage protease, Kuzbanian, which is critical for Notch activity. [Science Signaling] |
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| Employing consensus clustering analysis, scientists evaluated the correlations between epithelial cell marker genes, prognosis, and immune responses in prostate cancer. [Journal Of Translational Medicine] |
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| The implications of binding competition of vanadates(V) with dodecyl sulfates for bovine serum albumin on cytotoxicity of vanadium(V) species against prostate cancer cells were investigated. [International Journal Of Biological Macromolecules] |
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| Scientists showed that semaphorin 3C, a secreted signaling protein that is highly expressed in castration-resistant prostate cancer, could promote steroidogenesis by altering the expression profile of key steroidogenic enzymes. [Endocrine-Related Cancer] |
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| The cytotoxic effects of Ganoderma lucidum polysaccharide in combination with docetaxel and flutamide on prostate cancer cells were investigated by the MTT test, Hoechst staining, and flow cytometry. [Scientific Reports] |
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| The authors provide an overview of the design, preparation, methodology, and oncological aspects of organic polymeric nanoparticles-based photodynamic therapy for the treatment of prostate cancer. [ACS Materials Au] |
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| As shortages of drugs like amoxicillin, penicillin, Adderall and certain chemotherapies continue to confound doctors and patients in the US, two high-ranking Republican lawmakers are pressing the FDA for answers. [Fierce Pharma] |
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| December 16 – 20, 2023 Waikoloa Beach, Hawaii, United States |
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| University of Cambridge – Cambridge, England, United Kingdom |
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| Fred Hutchinson Cancer Center – Seattle, Washington, United States |
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| Cedars-Sinai – Los Angeles, California, United States |
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| Cedars-Sinai – Los Angeles, California, United States |
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| University of Southern California – Los Angeles, California, United States |
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