 | | Vol. 15.00 – 5 January, 2024 |
| |
|
|
| CRPC drugs work by either reducing dihydrotestosterone biosynthesis, or blocking androgen receptor (AR) signaling. Investigators demonstrated that AR inhibitor treatment gave rise to a drug-tolerant persister state.
[Advanced Science] |
|
|
|
 | | PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| The authors showed that peroxisome proliferator-activated receptor α (PPARα) acted downstream of PIM1 kinase to accelerate lipid droplet accumulation and promote cell proliferation in prostate cancer.
[Oncogene] |
|
|
|
| In vitro studies demonstrated that Myeloid differentiation factor-2 conferred invasiveness by activating MAPK and NF-kB signaling pathways and inducing epithelial–mesenchymal transition.
[Oncogene] |
|
|
|
| In an attempt to understand how aberrant cAMP signaling drives prostate cancer growth, scientists immunopurified PDE4D7 and identified binding proteins by mass spectrometry.
[Molecular Oncology] |
|
|
|
| Samples were harvested to validate the expression of EZH2, miR-26a-5p, and IL-6, and the protein and its phosphorylation of STAT3 were assessed in prostate cancer cells.
[Expert Opinion On Therapeutic Targets] |
|
|
|
| To study the precise activities and action mechanisms of NOTCH3 in docetaxel-resistant prostate cancer, immunoprecipitation, mass spectrometry, ChIP, luciferase reporter assay, cell metabolism, and animal experiments were performed.
[Cancer Science] |
|
|
|
| Scientists demonstrated that Sinularin inhibited the viability of human prostate cancer cells in a dose-dependent manner and displayed significant cytotoxicity only at high concentration against normal prostate epithelial cell RWPE-1.
[Biochemical Pharmacology] |
|
|
|
| Using bioinformatic analysis of data from the most recent databases, investigators extensively elucidated the role played by COL10A1 in terms of its expression patterns, prognostic implications, and immune efficacy across a pan-cancer spectrum.
[Aging-Us] |
|
|
|
| PSMA was isolated from pooled seminal plasma from low-risk grade Groups 1 and 2 prostate cancer patients. Intact glycopeptides were analyzed by mass spectrometry to identify site-specific glycoforms.
[The Prostate] |
|  |
|
|
|
| Scientists studied the molecular markers most associated with prostate cancer circulating tumor cells to better understand their function on tumorigenesis and metastatic cascade, the methodologies utilized to analyze these biomarkers, and their clinical significance.
[Critical Reviews In Oncology Hematology] |
|
|
|
|
| The expected price hikes come as the pharmaceutical industry gears up for the Biden Administration to publish significantly discounted prices for ten high-cost drugs in September, and continues to contend with higher inflation and manufacturing costs.
[Reuters] |
|
|
|
|
| March 11 – 13, 2024
Lisbon, Portugal |
|
|
|
|
|
| | Cedars-Sinai – Los Angeles, California, United States |
|
|
|
| | Human Technopole – Milan, Itlay |
|
|
|
| | Jefferson-Sidney Kimmel Cancer Center – Philadelphia, Pennsylvania, United States |
|
|
|
| | MD Anderson Cancer Center – Houston, Texas, United States |
|
|
|
| | Pfizer – Multiple Locations, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
