 | | Vol. 15.03 – 26 January, 2024 |
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| Investigators demonstrated that high CD93 expression in the tumor vessels was closely related to the poor immune response of prostate cancer.
[Advanced Materials] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| A new type of pH-responsive dual androgen-blocking nanodrug based on a molecularly imprinted polymer was designed and synthesized, and could selectively sequester testosterone from the prostate tumor.
[ACS Applied Materials & Interfaces] |
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| Different cellular/molecular/preclinical approaches with human prostate cancer-samples, and in vitro/in vivo prostate cancer-models were used to comprehensively characterize the RNA-Exosome-complex profile and explore its role in prostate cancer.
[Cancer Letters] |
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| The authors discovered that CYLD inhibited tumor cell proliferation and enhanced the sensitivity to cell ferroptosis in prostate cancer in vitro and in vivo, respectively.
[Cell Death & Disease] |
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| SET and MYND domain containing protein 2 (SMYD2) knockdown dramatically inhibited the proliferation, migration, invasion, and epithelial-mesenchymal transition potential of 22Rv1 and C4-2 cells.
[Oncogene] |
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| AZD1775 resulted in rapid and potent cell killing with comparable IC50s across different prostate cancer cell lines, while SRA737 displayed time-dependent progressive cell killing with 10- to 20-fold differences in IC50s.
[Oncogene] |
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| Investigators found that lncRNA SNHG3, a highly expressed lncRNA in CRPC via bioinformatics analysis, promoted the invasive ability and the Enz resistance of the prostate cancer cells.
[International Journal Of Biological Macromolecules] |
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| Researchers reported a multifunctional gold nanoprobe-based thermophoretic assay for simultaneous specific distinguishing of prostate cancer circulating tumor cells and sensitive imaging of intracellular microRNA, achieving the rapid and precise detection of prostate cancer.
[Analytical Chemistry] |
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| Scientists studied molecular details prodded by the change of extracellular zinc by employing a panel of normal and cancerous breast and prostate cell lines coupled with the top-down proteomics with two-dimensional gel electrophoresis followed by liquid chromatography-tandem mass spectrometry.
[Journal Of Oncology] |
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| The authors delve into the implications of oncometabolite accumulation in prostate cancer, centering their focus on the consequential epigenetic alterations and impacts on cancer stem cells (CSCs), with the ultimate goal of outlining novel therapeutic strategies.
[Cell Communication And Signaling] |
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| The US Environmental Protection Agency (EPA) has abandoned a controversial plan to phase out all use of mammals to test the safety of chemicals by 2035. The hard deadline—imposed in 2019 to accelerate a move toward nonanimal models such as computer programs and “organs on a chip”—made EPA unique among US federal agencies.
[Science Insider] |
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| March 18 – 19, 2024
London, England, United Kingdom |
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| | Pfizer – Multiple Locations, United States |
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| | Karolinska Institutet – Solna, Sweden |
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| | The Vancouver Prostate Centre – Vancouver, British Columbia, Canada |
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| | Human Technopole – Milan, Italy |
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| | Jefferson-Sidney Kimmel Cancer Center – Philadelphia, Pennsylvania, United States |
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