 | | Vol. 15.08 – 1 March, 2024 |
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| The authors intersected circulating tumor DNA fraction, treatment outcomes, and clinical characteristics across 738 plasma samples from 491 male metastatic CRPC patients from two randomized multicentre Phase II trials and a prospective province-wide blood biobanking program.
[Nature Communications] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers derived molecular subtypes of prostate cancer using gene expression analysis of localized prostate cancer samples from prostatectomy patients and validated these subtypes in two independent prostatectomy cohorts.
[NPJ Precision Oncology] |
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| Investigators found that phenyllactic acid (PLA) was detected in all prostate cancer cell lines. Further experiments showed that the addition of PLA to prostate cancer cells could promote ATP generation, enhance cysteine desulfurase expression, and reduce tumor necrosis factor alpha levels.
[International Journal Of Biochemistry & Cell Biology] |
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| The authors performed a lncRNA-focused analysis of single-cell RNA-sequencing data (n = 14) from Metastatic castration-resistant prostate cancer biopsies followed by integration with bulk multi-omic datasets.
[Prostate Cancer And Prostatic Diseases] |
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| Scientists examined the relationship between hyperglycemia and miRNA levels in PCa. Relative expression of urinary miR-574-3p, miR-375, miR-205-5p, miR-200b-3p, miR-187-3p, miR-182-5p, and miR-100-5p were investigated in 105 PCa patients and 138 noncancer controls by Real-Time quantitative PCR.
[Prostate Cancer And Prostatic Diseases] |
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| The authors investigated the genomic evolution of prostate cancer through the application of three separate classification methods, each designed to investigate a different aspect of tumor evolution.
[Cell Genomics] |
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| Scientists systematically review the impact of hormonal changes that occur during aging on the prostate, including the role of sex hormones, insulin-like growth factor 1, thyroid hormones, and insulin.
[Frontiers In Endocrinology] |
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| The American Urological Association, in partnership with the American Society for Radiation Oncology and the Society of Urologic Oncology, released the 2024 clinical practice guideline on salvage therapy for prostate cancer.
[American Urological Association (GlobeNewswire, Inc.)] |
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| April 7 – 10, 2024
San Diego, California, United States |
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| | Indiana University School of Medicine – Indianapolis, Indiana, United States |
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| | Augusta University – Augusta, Georgia, United States |
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| | The Henry M. Jackson Foundation – Bethesda, Maryland, United States |
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| | UC Davis – Davis, California, United States |
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| | Cyprus Cancer Research Institute – Aglandjia, Cyprus |
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