Progression of Prostate Carcinogenesis and Dietary Methyl Donors: Temporal Dependence Researchers looked at the effect of excess methyl donors on the growth rate of prostate cancer (PCa) in vivo, the ability of 5-aza-2′-deoxycytidine to demethylate in the presence of excess dietary methyl donors and the effect of in utero feeding of excess methyl donors to the later onset of PCa. [Cancer Prev Res] Abstract