 | | Vol. 10.07 – 25 February, 2021 |
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| Investigators tested the direct effect of triciribine on angiotensin‐converting enzyme 2 (ACE2) expression in human bronchial and lung alveolar epithelial cells.
[Journal of Cellular Physiology] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| In vitro alveolar epithelial cells consistently exhibited a significant induction of reticulocalbin 3 accompanied with NFκB activation in response to LPS exposure.
[American Journal of Physiology-Lung Cellular and Molecular Physiology] |
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| BEAS-2B cells were exposed to house dust mite and the expressions of PGC-1α and E-cadherin were examined by immunoblotting.
[Respiratory Research] |
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| Human bronchial epithelial brushing from patients with and without COPD were cultured into air–liquid interface cultures and treated with or without olodaterol and respiratory syncytial virus infection to examine the effect on markers of inflammation including interleukin-8 and mucus secretion.
[Respiratory Research] |
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| Scientists evaluated the impact of down-regulation of LINK-A in A549 and Calu-3 cell lines as cellular models of NSCLC.
[Scientific Reports] |
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| Investigators clarified the role of neuron-specific enolase (NSE) in the progression of SCLC and found that NSE expression was positively correlated with distant metastasis.
[Translational Oncology] |
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| Researchers investigated the expression of ZNF674-AS1 in 83 pairs of NSCLC specimens and adjacent noncancerous lung tissues. The clinical significance of ZNF674-AS1 in NSCLC was analyzed.
[Cellular & Molecular Biology Letters] |
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| The biological roles of pentraxin 3 in NSCLC progression and NSCLC cell resistance to cisplatin were evaluated using enzyme-linked immunosorbent assay, cell count kit-8, colony formation assay, flow cytometry, as well as xenograft tumor assay.
[Archives of Biochemistry and Biophysics] |
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| RT‐qPCR was used to measure the expression of genes. Actinomycin D and RNase R were employed to examine the stability of circVAPA. CCK‐8, EdU, Transwell, sphere formation assay, and western blot analysis were conducted to examine the changes of NSCLC cells in response to circVAPA knockdown.
[Journal of Gene Medicine] |
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| The authors summarize the role of alveolar fibroblasts and their activation stage in alveolar septation and regeneration and incorporate them into the context of human lung disease, discussing fibroblast activation stages and how they contribute to bronchopulmonary dysplasia, idiopathic pulmonary fibrosis, and COPD.
[Stem Cells Translational Medicine] |
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| The Lung Cancer Research Foundation announced a collaboration with AstraZeneca to fund over $900,000 in research grants focused on understanding resistance to epidermal growth factor receptor tyrosine kinase inhibitors and immune checkpoint inhibitors, including therapeutic approaches to overcome these mechanisms, as well as biomarkers of immune-mediated adverse events.
[Lung Cancer Research Foundation] |
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| June 21 – 26, 2021
Virtual |
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| | UT Health Science Center at Tyler – Tyler, Texas, United States |
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| | The Francis Crick Institute – London, England, United Kingdom |
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| | University of California, San Francisco – San Francisco, California, United States |
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| | H. Lee Moffitt Cancer Center & Research Institute – Tampa, Florida, United States |
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| | Gilead Sciences, Inc. – Foster City, California, United States |
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