 | | Vol. 11.01 – 13 January, 2022 |
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| Researchers demonstrated that the levels of acid phosphatase 5 were increased in idiopathic pulmonary fibrosis patient samples and mice with bleomycin-induced pulmonary fibrosis.
[Nature Communications] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists performed colony formation assays, soft-agar assays, and tumor growth in nude mice to show that 100 mg/L Nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) facilitated the malignant transformation of human bronchial epithelial Beas-2B cells.
[Toxicology and Applied Pharmacology] |
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| The authors evaluated the effects of the association between Cryptococcus neoformans and Dermatophagoides pteronyssinus in the modulation of airway inflammatory responses in an in vitro experimental model using human bronchial epithelial cells.
[Inflammation] |
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| Wistar rats were treated with nickel oxide nanoparticles (NiO NPs) suspensions by intratracheal instillation twice-weekly for nine weeks. A549 cells were treated with NiO NPs suspensions for 24 hours.
[Environmental Toxicology] |
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| The altered expression of microRNAs has been found in asthma. Researchers elucidated the mechanisms responsible for the effects of miR‑375 on Dex‑induced airway epithelial cell dysfunction.
[International Journal of Molecular Medicine] |
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| Investigators identified neurokinin-1 as a significantly upregulated GPCR in the transcriptome and tissue array of human lung cancer samples, associated with advanced clinical stages and poor prognosis.
[Cell Death & Disease] |
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| Gain- and loss- of function assay verified the impact of circ-PITX1 and miR-30e-5p on the proliferation, invasion, and migration of NSCLC cells.
[Cell Cycle] |
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| Researchers investigated the anti-cancer effects of boric acid, sodium pentaborate pentahydrate, and sodium perborate tetrahydrate against SCLC cell line DMS-114 cells in vitro.
[Journal of Trace Elements in Medicine and Biology] |
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| Scientists established gefitinib-resistant NSCLC cells. The levels of circ_MACF1, microRNA-942-5p, and transforming growth factor beta receptor 2 were gauged by quantitative real-time PCR or western blot.
[BMC Pulmonary Medicine] |
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| The effects of erufosine in NSCLC cell line A549 and SCLC cell line DMS 114 in terms of cell viability, induction of apoptosis, cell cycle phase distribution, gene and protein expression levels, and migration capacity were investigated.
[Molecular Biology Reports] |
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| Scientists discuss recent developments in our understanding of lung macrophage heterogeneity, ontogeny, metabolism and function in the context of health and disease, and highlight core conceptual advances and key unanswered questions that should be focus of work in the coming years.
[Mucosal Immunology] |
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| On Target Laboratories, Inc., announced the completion of Phase III, randomized, multi-center, single-dose, open-label ELUCIDATE Trial, which investigated the use of CYTALUX injection in patients scheduled to undergo thoracic surgery for confirmed or suspected cancer in the lung.
[On Target Laboratories, Inc. (CISION PR Newswire)] |
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| February 10 – 12, 2022
Lorne, Victoria, Australia |
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| Albert Einstein College of Medicine – Bronx, New York, United States |
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| Fox Chase Cancer Center, Temple University – Philadelphia, Pennsylvania, United States |
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| Baylor College of Medicine – Houston, Texas, United States |
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| National Institutes of Health – Bethesda, Maryland, United States |
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| Indiana University School of Medicine – Indianapolis, Indiana, United States |
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