Pulmonary Cell News Volume 11.32 | Aug 18 2022

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    2022-08-18 | ICN 11.32


    Pulmonary Cell News by STEMCELL Technologies
    Vol. 4.30 – 18 August, 2022
    TOP STORY

    Spatially Resolved Deconvolution of the Fibrotic Niche in Lung Fibrosis

    Researchers confirmed findings through bioinformatic, tissue, and in vitro analyses, identifying that loss of NFKB inhibitor zeta in alveolar epithelial cells dysregulated the TGFβ/IL-6 signaling axis, which may impair homeostatic responses to environmental stress.
    [Cell Reports]

    Full ArticleGraphical Abstract
    Explore Antibodies for Epithelial Cell Markers
    PUBLICATIONSRanked by the impact factor of the journal

    Puerarin Ameliorates Acute Lung Injury by Modulating NLRP3 Inflammasome-Induced Pyroptosis

    The interaction between HDAC1 and PP2A as well as between PP2A and NLRP3 was analyzed.
    [Cell Death Discovery]

    Full Article

    Acetate, a Gut Bacterial Product, Ameliorates Ischemia-Reperfusion Induced Acute Lung Injury in Rats

    Scientists examined whether short-chain fatty acids had protective effects against ischemia-reperfusion-induced acute lung injury and explored possible protective mechanisms.
    [International Immunology]

    Abstract

    CircRNA 0009043 Suppresses Non-Small-Cell Lung Cancer Development via Targeting the miR-148a-3p/DNAJB4 Axis

    The expression of circ_0009043, miR-148a-3p, and DnaJ heat shock protein family member B4 in NSCLC cells was assessed via qPCR.
    [Biomarker Research]

    Full Article

    Upregulation of KLHL17 Promotes the Proliferation and Migration of Non-Small Cell Lung Cancer by Activating the Ras/MAPK Signaling Pathway

    Scientists explored the role of Kelch-like 17 (KLHL17) in the development and progression of NSCLC.
    [Laboratory Investigation]

    Abstract

    METTL3-Induced DLGAP1-AS2 Promotes Non-Small Cell Lung Cancer Tumorigenesis through m6A/C-Myc-Dependent Aerobic Glycolysis

    Researchers focused on the functions and molecular mechanism of m6A-modified lncRNA DLGAP1 antisense RNA 2 (DLGAP1-AS2) in NSCLC.
    [Cell Cycle]

    Abstract

    An ISSCR 2022 Innovation Showcase Webinar: Reliable In Vitro Culture Solutions for Your Alveolar Research, presented by Dr. Johanna Finn. Click to Watch Now.
    REVIEWS

    Role of Necroptosis in Airflow Limitation in Chronic Obstructive Pulmonary Disease: Focus on Small-Airway Disease and Emphysema

    Investigators review the correlations of small-airway disease and emphysema with airflow limitation in COPD and analyze the effects of necroptosis on small-airway disease and emphysema.
    [Cell Death Discovery]

    Full Article
    INDUSTRY AND POLICY NEWS

    Novartis Provides Update on Phase III CANOPY-A Study Evaluating Canakinumab as Adjuvant Treatment in Non-Small Cell Lung Cancer

    Novartis announced that the Phase III CANOPY-A study evaluating adjuvant treatment with canakinumab, an inhibitor of interleukin-1beta, in adult patients with stages II-IIIA and IIIB completely resected NSCLC did not meet its primary endpoint of disease-free survival versus placebo
    [Novartis]

    Press Release
    FEATURED EVENT

    COVID and Beyond: Novel Approaches to Global Infectious Diseases

    October 26 – 29, 2022
    Brussels, Belgium

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    JOB OPPORTUNITIES

    Postdoctoral Position – Lung Cancer

    NYU Langone Health – New York, New York, United States

    Senior Investigator – Cancer Research

    NIH National Cancer Institute – Bethesda, Maryland, United States

    Postdoctoral Researcher – Lung Cancer and Lymphoma

    University of Cologne – Cologne, Germany

    Postdoctoral Fellowship – Translational Cardiovascular Medicine

    University of Alberta – Edmonton, Alberta, Canada

    Lecturer/Senior Lecturer – Immunomodulation

    King’s College London – London, United Kingdom

    > See All Jobs

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